| Revista: | Revista brasileira de ciencia avicola |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000279276 |
| ISSN: | 1516-635X |
| Autores: | Ito, Nair Massako Katayama1 Miyaji, Claudio Issamu Scanavini-Neto, Hugo2 Lima, E. de A Okabayashi, S Correa, A.R.A Eleuterio, G.C Zuanaze, M.A |
| Instituciones: | 1Universidade de Santo Amaro, Faculdade de Medicina Veterinaria, Santo Amaro, Sao Paulo. Brasil 2Laboratorios Biovet, Sao Paulo. Brasil |
| Año: | 2004 |
| Periodo: | Ene-Mar |
| Volumen: | 6 |
| Número: | 1 |
| Paginación: | 41-54 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Nota breve o noticia |
| Enfoque: | Experimental |
| Resumen en inglés | IBDV Gm 11 (Simbios eleven-molecular group) has been detected since 1997 in many farms of commercial broilers and layers causing high mortality (2 to 15%) and severe macro and microscopic damage in cloacal bursae, spleen, thymus, kidney and liver. Five serial passages of 2050/97-Gm 11 IBDV sample by CAM route in SPF chicken's embryonated eggs did not elicit increased embryo mortality. High mortality (100%) of 21 day-old SPF leghorn chickens and severe bursal and splenic lesions were seen from 24 up to 48 hours after eye-drop inoculation of 2050/97 strain (50 mL of 10-2 dilution of 10% bursae homogenate). Mortality was not detected when vaccinated SPF and broiler chickens were inoculated. One dead bird was found among ten challenged unvaccinated broilers. Variations in the intensity of cloacal bursae injury and spleen response were found between unvaccinated and vaccinated broiler chickens. IBDV antibodies were detected by ELISA test in almost all vaccinated SPF chickens before challenge while low number of commercial vaccinated and unvaccinated broilers were serologically positive (0 to 3 birds in 18). Increasing IBDV antibody titers were detected after challenge with 2050/97 strain and highest GMTs were found in broilers. It was concluded that 2050/97 strain is a highly virulent IBDV and SPF leghorn chickens immunized with BV8 intermediate vaccine strain were resistant to the challenge. Increasing susceptibility was found from experimental groups of unvaccinated broilers to vaccinated broilers and to unvaccinated SPF birds. It is |
| Disciplinas: | Medicina veterinaria y zootecnia |
| Palabras clave: | Aves de corral, Medicina veterinaria, Pollos de engorda, Histopatología, Bursitis, Virus, Vacunas, Serología |
| Keyword: | Veterinary medicine and animal husbandry, Poultry, Veterinary medicine, Histopathology, Bursitis, Virus, Vaccines, Serology |
| Texto completo: | Texto completo (Ver HTML) |
