| Revista: | Pesquisa veterinaria brasileira |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000301608 |
| ISSN: | 0100-736X |
| Autores: | Aguirre, José Ignacio1 Gomar, María Soledad Igal, Silvio Quiroga, María Alejandra Portiansky, Enrique Leo Gimeno, Eduardo Juan |
| Instituciones: | 1Universidad Nacional de La Plata, Facultad de Ciencias Veterinarias, La Plata, Buenos Aires. Argentina |
| Año: | 2005 |
| Periodo: | Ene-Mar |
| Volumen: | 25 |
| Número: | 1 |
| Paginación: | 34-38 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Experimental |
| Resumen en inglés | The aim of this study was to describe the bone changes observed after a daily oral administration of the calcinogenic plant Solanum malacoxylon (syn. S. glaucophyllum) (Sm) during 9 days. The Sm-poisoned rabbits had an increase of bone resorption in the endosteal surface of the cortical zone and also in the surface covered by osteoblasts of the primary and secondary spongiosa of the trabecular bone compartment. Moreover, the epiphyseal growth plates in long bones appeared narrower than in the control rabbits, with reduction of the proliferative and hyperthrophic chondrocyte zones. The electron microscopic study revealed a significant decrease of proteoglycans in the hyperthrophic chondrocyte zone evidenced by a significant reduction of rutenium red positive granules in the poisoned rabbit. Altogether, these data suggest that cell differentiation may play a pivotal role in the pathogenesis of Sm-induced bone lesions |
| Disciplinas: | Medicina veterinaria y zootecnia, Biología |
| Palabras clave: | Medicina veterinaria, Nutrición animal, Otras especies de interés zootécnico, Botánica, Conejos, Solanum malacoxylon, Solanum glaucophyllum, Tejido óseo, Plantas tóxicas, Intoxicación experimental, Placa de crecimiento |
| Keyword: | Veterinary medicine and animal husbandry, Biology, Animal nutrition, Species of commercial interest, Veterinary medicine, Botany, Rabbits, Solanum malacoxylon, Solanum glaucophyllum, Bone tissue, Growth plate, Toxic plants, Experimental intoxication |
| Texto completo: | Texto completo (Ver HTML) |
