| Revista: | Perinatología y reproducción humana |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000360685 |
| ISSN: | 0187-5337 |
| Autores: | Reyna Ríos, Edna Rocely1 Fernández Carrocera, Luis Alberto1 Salinas Ramírez, Vicente2 Echaniz Avilés, Olga1 Romero Maldonado, Silvia1 |
| Instituciones: | 1Instituto Nacional de Perinatología Isidro Espinosa de los Reyes, México, Distrito Federal. México 2Instituto de Salud del Estado de México, Hospital Materno Perinatal "Mónica Pretelini Sáenz", Toluca, Estado de México. México |
| Año: | 2011 |
| Periodo: | Oct-Dic |
| Volumen: | 25 |
| Número: | 4 |
| Paginación: | 219-223 |
| País: | México |
| Idioma: | Español |
| Tipo de documento: | Artículo |
| Enfoque: | Experimental, caso clínico |
| Resumen en español | horas de ventilación mecánica y los casos de DBP y ROP además de la necesidad de aplicación de dosis adicionales |
| Resumen en inglés | Respiratory distress syndrome (RDS) is the principal respiratory problem in premature infants with high morbidity and mortality, due to immaturity and lack of production of pulmonary surfactant. Objective: Establish differences (incidence of RDS, intraventricular hemorrhage, broncopulmonar dysplasia, ventilation time and death) in the profi lactic treatment between two types of natural surfactant (porcine and bovine) in preterm infants. Material and methods: Cross sectional, retrospective and analytic study from July 2005 to July 2006. The inclusion criteria were: birth weight between 600- 1250 g, gestational age less than 32 weeks, orotraqueal intubation and hemodynamic stability, included in two groups: group 1 (poractant alfa 200 mg/ kg/doses) and group 2 (beractant 100 mg/kg/doses). Birthweight, gestational age, FiO2 , ventilation time, RDS, BPD, intraventricular hemorrhage, ROP and mortality were analysed. Statistical analysis was done with SPSS 15, using, depending the type of variable, chi cuadrada, t de Student, U de Mann-Whitney and OR (CI 95%). Results: In the poractant alfa group there were 74 cases, and beractant group 80. The requirement of FiO2 , ventilation time, cases of RDS, DBP, ROP, and the association of RDS with mortality were less for poractant alfa group, and they only received one dosis in the 83% of the cases. These differences were statistical signifi cant. Conclusions: The use of poractant alfa reduces the risk of developing RDS, the percentage of FiO2 required, hours of mechanical ventilation and BPD, as well as the need for further doses |
| Disciplinas: | Medicina |
| Palabras clave: | Neumología, Pediatría, Terapéutica y rehabilitación, Surfactantes, Prematuros, Síndrome de dificultad respiratoria, Recién nacidos |
| Keyword: | Medicine, Pediatrics, Pneumology, Therapeutics and rehabilitation, Surfactants, Premature children, Respiratory distress syndrome, Newborn |
| Texto completo: | Texto completo (Ver PDF) |
