| Revista: | Memorias do Instituto Oswaldo Cruz |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000415593 |
| ISSN: | 0074-0276 |
| Autores: | Soares, Rodrigo Pedro1 Nogueira, Paula Monalisa1 Secundino, Nagila Francinete1 Marialva, Eric Fabricio2 Ríos Velásquez, Claudia Maria2 Pessoa, Felipe Arley Costa2 |
| Instituciones: | 1Fundacao Oswaldo Cruz, Instituto Rene Rachou, Belo Horizonte, Minas Gerais. Brasil 2Fundacao Oswaldo Cruz, Instituto Leonidas e Maria Deane, Manaus, Amazonas. Brasil |
| Año: | 2018 |
| Periodo: | Mar |
| Volumen: | 113 |
| Número: | 3 |
| Paginación: | 202-205 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Experimental, aplicado |
| Resumen en inglés | Lutzomyia umbratilis, the vector for Leishmania guyanensis in northern South America, has been found naturally infected with L. guyanensis only in areas north of the Negro and Amazon rivers. While populations of this sand fly species are also found in areas south of these rivers, these populations have never been reported to be infected and/or transmitting L. guyanensis. However, no studies on the corresponding host-parasite interactions are available. OBJECTIVES This study evaluated the interaction between Lu. guyanensis promastigotes and field-collected Lu. umbratilis sand flies from Rio Preto da Eva and Manacapuru, which are located to the north and south, respectively, of the Negro River. METHODS Procyclic and metacyclic attachment was quantified using an in vitro system. FINDINGS Low attachment of parasites to the midguts of insects collected from Manacapuru was detected. Conversely, greater binding of metacyclic parasites was observed in the midguts of insects collected from Rio Preto da Eva, and this attachment was more pronounced than that observed for procyclics (p < 0.03). MAIN CONCLUSIONS The Lu. umbratilis population from an area south of the Negro River has lower in vitro interaction with L. guyanensis. The higher attachment of L. guyanensis to midguts of insects from Rio Preto da Eva may suggest better vector competence. These findings are in accordance with previously reported epidemiological information of American cutaneous leishmaniasis (ACL) transmission in the Amazon |
| Disciplinas: | Medicina |
| Palabras clave: | Salud pública, Parasitología, Insectos, Leishmaniasis cutánea americana, Vectores biológicos, Lutzomyia umbratilis, Leishmania guyanensis |
| Keyword: | Medicine, Microbiology, Public health, Insects, American cutaneous leishmaniasis, Biological vectors, Lutzomyia umbratilis, Leishmania guyanensis, Parasitology |
| Texto completo: | Texto completo (Ver HTML) |
