| Revista: | Memorias do Instituto Oswaldo Cruz |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000452394 |
| ISSN: | 0074-0276 |
| Autores: | Zabala Peñafiel, Anabel1 Fantinatti, Maria1 Dias Lopes, Geovane1 da Silva, Jéssica Leite1 Miranda, Luciana de Freitas Campos2 Lyra, Marcelo Rosandiski2 Pimentel, Maria Inês Fernandes2 Conceição Silva, Fátima1 Alves, Carlos Roberto1 |
| Instituciones: | 1Fundacao Oswaldo Cruz, Instituto Oswaldo Cruz, Rio de Janeiro. Brasil 2Fundacao Oswaldo Cruz, Instituto Nacional de Infectologia Evandro Chagas, Rio de Janeiro. Brasil |
| Año: | 2022 |
| Volumen: | 117 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Aplicado, descriptivo |
| Resumen en inglés | BACKGROUND Leishmania parasites carry a double-stranded RNA virus (Leishmania RNA virus - LRV) that has been divided in LRV1 and LRV2. OBJECTIVES Leishmania (Viannia) braziliensis clinical isolates were assessed in order to determine LRV presence. METHODS Two-round polymerase chain reaction (PCR and nested PCR) was performed to detect LRV1 or LRV2 in L. (V.) braziliensis clinical isolates (n = 12). FINDINGS LRV1 was detected in three clinical isolates which was phylogenetically related to other sequences reported from other American tegumentary leishmaniasis (ATL) endemic areas of Brazil. Patients infected with L. (V.) braziliensis LRV-negative showed only cutaneous lesions while LRV-positive reported different manifestations. MAIN CONCLUSION Data presented here show for the first time that LRV1 is circulating in L. (V.) braziliensis clinical isolates from Rio de Janeiro State in Brazil |
| Disciplinas: | Medicina |
| Palabras clave: | Parasitología, Epidemiología, Genética, ARN viral, Nuevos registros, Leishmania braziliensis, Brasil |
| Keyword: | Parasitology, Epidemiology, Genetics, Viral RNA, New records, Leishmania braziliensis, Brazil |
| Texto completo: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
