| Revista: | Memorias do Instituto Oswaldo Cruz |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000352210 |
| ISSN: | 0074-0276 |
| Autores: | Fagundes, Aline1 Marzochi, Mauro C.A1 Fernandes, Octavio2 Perez, Mauricio A3 Schubach, Armando de Oliveira4 Schubach, Tania M.P4 Amendoeira, Maria Regina Reis5 Mouta-Confort, Eliame1 Marzochi, Keyla Belizia Feldman1 |
| Instituciones: | 1Fundacao Instituto Oswaldo Cruz, National Reference Center for Diagnosis of Tegumentary Leishmaniasis, Rio de Janeiro. Brasil 2Fundacao Instituto Oswaldo Cruz, Laboratorio de Epidemiologia Molecular de Doencas Infecciosas, Rio de Janeiro. Brasil 3Universidade Federal do Rio de Janeiro, Departamento de Medicina Preventiva, Rio de Janeiro. Brasil 4Fundacao Instituto Oswaldo Cruz, Department of Infectious Diseases, Rio de Janeiro. Brasil 5Fundacao Instituto Oswaldo Cruz, Laboratorio de Toxoplasmose, Rio de Janeiro. Brasil |
| Año: | 2007 |
| Periodo: | Dic |
| Volumen: | 102 |
| Número: | 8 |
| Paginación: | 1003-1005 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Experimental |
| Resumen en inglés | The objective of the present study was to evaluate the specificity of the Montenegro skin test (MST) in an area in Brazil, state of Grande do Sul State (RS), which was considered to be non-endemic for leishmaniasis. Sixty subjects presented a positive MST and were reevaluated by clinical examination, serology and polymerase chain reaction (PCR) of peripheral blood for the detection of subclinical Leishmania infection. None of the subjects presented clinical signs or symptoms of current leishmaniasis or a history of the disease. Leishmania (Viannia) DNA was detected in blood by PCR and hybridization in one subject. The PCR skin test-positive individual remained asymptomatic throughout the study. Clinical examination showed no scars suggestive of past cutaneous leishmaniasis. Human subclinical infection with Leishmania (Viannia) in RS was confirmed by PCR. This is the first report of subclinical infection with this parasite in the human population of this area |
| Disciplinas: | Biología, Química, Medicina |
| Palabras clave: | Protozoarios, Bioquímica, Dermatología, Leishmania, Reacción en cadena de la polimerasa (PCR), Prueba cutánea de Montenegro, Infección subclínica, Rio Grande do Sul, Brasil |
| Keyword: | Biology, Chemistry, Medicine, Protozoa, Biochemistry, Dermatology, Protozoans, Leishmania, Polymerase chain reaction (PCR), Montenegro skin test, Subclinical infection, Rio Grande do Sul, Brazil |
| Texto completo: | Texto completo (Ver PDF) |
