Congenital transmission of Trypanosoma cruzi in central Brazil. A study of 1,211 individuals born to infected mothers



Título del documento: Congenital transmission of Trypanosoma cruzi in central Brazil. A study of 1,211 individuals born to infected mothers
Revista: Memorias do Instituto Oswaldo Cruz
Base de datos: PERIÓDICA
Número de sistema: 000392305
ISSN: 0074-0276
Autores: 1
1
1
1
1
1
1
Instituciones: 1Universidade Federal de Goias, Nucleo de Estudos de Doenca de Chagas, Goiania, Goias. Brasil
Año:
Periodo: May
Volumen: 110
Número: 3
Paginación: 369-376
País: Brasil
Idioma: Inglés
Tipo de documento: Estadística o encuesta
Enfoque: Analítico
Resumen en inglés Transmission of Trypanosoma cruzi during pregnancy is estimated to occur in less than 20% of infected mothers; however, the etiopathogenesis is not completely understood. The Centre for Studies on Chagas Disease provides confirmation of T. cruzi infection for individuals living in central Brazil. In this retrospective hospital-based study, all requests for diagnosis of T. cruzi infection in individuals less than 21 years old from 1994-2014 were searched. We end with 1,211 individuals and their respective infected mothers. Congenital transmission of infection was confirmed in 24 individuals (2%) in central Brazil, an area where the main T. cruzi lineage circulating in humans is TcII. This low prevalence of congenital Chagas disease is discussed in relation to recent findings in the south region of Brazil, where TcV is the main lineage and congenital transmission has a higher prevalence (approximately 5%), similar to frequencies reported in Argentina, Paraguay and Bolivia. This is the first report to show geographical differences in the rates of congenital transmission of T. cruzi and the relationship between the prevalence of congenital transmission and the type of Tc prevalent in each region
Disciplinas: Medicina
Palabras clave: Microbiología,
Salud pública,
Enfermedad de Chagas,
Transmisión congénita,
Trypanosoma cruzi,
Diferenciación geográfica,
Prevalencia
Keyword: Medicine,
Microbiology,
Public health,
Chagas disease,
Congenital transmission,
Trypanosoma cruzi,
Geographic differentiation,
Prevalence
Texto completo: Texto completo (Ver HTML)