Abdominal angiostrongyliasis can be diagnosed with a immunochromatographic rapid test with recombinant galactin from Angiostrongylus cantonensis
Título del documento: Abdominal angiostrongyliasis can be diagnosed with a immunochromatographic rapid test with recombinant galactin from Angiostrongylus cantonensis
Revista: Memorias do Instituto Oswaldo Cruz
Base de datos: PERIÓDICA
Número de sistema: 000437043
ISSN: 0074-0276
Autores: 1
2
3
3
4
4
Instituciones: 1Universidade Federal do Espirito Santo, Centro de Ciencias da Saude, Vitoria, Espirito Santo. Brasil
2Pontificia Universidade Catolica do Rio Grande do Sul, Escola de Ciencias da Saude, Porto Alegre, Rio Grande do Sul. Brasil
3Universidade de Passo Fundo, Passo Fundo, Rio Grande do Sul. Brasil
4Khon Kaen University, Faculty of Medicine and Mekong Health Science Research Institute, Khon Kaen. Tailandia
Año:
Volumen: 115
País: Brasil
Idioma: Inglés
Tipo de documento: Nota breve o noticia
Enfoque: Experimental, aplicado
Resumen en inglés Angiostrongylus costaricensis is the causative agent of abdominal angiostrongyliasis, a zoonotic infection that may produce severe eosinophilic enterocolitis or hepatitis in humans. Parasites are usually not released in stools and serology has an important role in diagnosis. Since cross-reactivity is demonstrated between A. costaricensis and another metastrongylid worm, A. cantonensis, we tested heterologous recombinant galectin as a probe in an immunochromatographic rapid diagnostic test (ICT-RDT) for detection of anti-A. costaricensis antibodies. Almost all (11/12) positive control sera from A. costaricensis infected patients were positive at ICT RDT. These are preliminary indications that r-galectin ICT-RDT is useful for diagnosing A. costaricensis infection
Disciplinas: Medicina
Palabras clave: Parasitología,
Diagnóstico,
Angiostrongiliasis abdominal,
Pruebas diagnósticas,
Prueba inmunocromatográfica,
Enterocolitis eosinofílica,
Hepatitis eosinofílica
Keyword: Parasitology,
Diagnosis,
Abdominal angiostrongyliasis,
Diagnostic tests,
Immunochromatographic tests,
Eosinophilic enterocolitis,
Eosinophilic hepatitis
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