A review of serological tests available in Brazil for intestinal schistosomiasis diagnosis



Título del documento: A review of serological tests available in Brazil for intestinal schistosomiasis diagnosis
Revista: Memorias do Instituto Oswaldo Cruz
Base de datos: PERIÓDICA
Número de sistema: 000459484
ISSN: 0074-0276
Autores: 1
2
2
2
1
Instituciones: 1Universidade Federal do Espirito Santo, Centro de Ciencias da Saude, Vitoria, Espirito Santo. Brasil
2Fundacao Oswaldo Cruz, Instituto Rene Rachou, Belo Horizonte, Minas Gerais. Brasil
Año:
Volumen: 118
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Aplicado, descriptivo
Resumen en inglés The World Health Organization (WHO) roadmap and recommendations for elimination of schistosomiasis were recently updated. With significant reductions in the prevalence and intensity of schistosomiasis infections worldwide, there is a need for more sensitive diagnostic methods. There are a few remaining transmission hotspots in Brazil, although low endemicity settings comprise most of the endemic localities. For the latter, serology may represent a tool for population screening which could help eliminate transmission of schistosomiasis. Here, we review serology tests currently available in Brazil from both public health and private laboratories: immunofluorescent antibody tests (IFATs) on adult worm sections and enzyme-linked immunosorbent assays (ELISAs) with soluble egg and adult worm antigens. Both in-house and commercially available tests have received less than adequate performance evaluations. Our review of immediate basic and operational research goals may help identify local adjustments that can be made to improve control interventions aimed at elimination of schistosomiasis as a public health problem
Disciplinas: Medicina
Palabras clave: Parasitología,
Diagnóstico,
Esquistosomiasis,
Serología,
Brasil
Keyword: Parasitology,
Diagnosis,
Schistosomiasis,
Serology,
Brazil
Texto completo: Texto completo (Ver HTML) Texto completo (Ver PDF)