Physico-chemical characterization of collagen scaffolds for tissue engineering



Título del documento: Physico-chemical characterization of collagen scaffolds for tissue engineering
Revista: Journal of applied research and technology
Base de datos: PERIÓDICA
Número de sistema: 000395672
ISSN: 1665-6423
Autores: 1
2
3
4
Instituciones: 1Universidad Nacional Autónoma de México, Facultad de Medicina, México, Distrito Federal. México
2Universidad Nacional Autónoma de México, Facultad de Odontología, México, Distrito Federal. México
3Universidad Nacional Autónoma de México, Centro de Ciencias Aplicadas y Desarrollo Tecnológico, México, Distrito Federal. México
4Universidad Nacional Autónoma de México, Instituto de Investigaciones en Materiales, México, Distrito Federal. México
Año:
Periodo: Feb
Volumen: 14
Número: 1
Paginación: 77-85
País: México
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Aplicado, descriptivo
Resumen en inglés The objective was to research the physical and chemical properties of collagen scaffolds (CS) obtained from bone matrix Nukbone(r) subject to a demineralization process using hydrochloric acid. The CS samples were characterized by optical and scanning electron microscopy, elemental chemical analysis, X-ray diffraction, spectroscopy Infrared, thermal analysis, differential scanning calorimetry and nitrogen adsorption. The microanalysis were used to set the macro- and microstructures of CS. They showed that the CS retained the morphology of Nukbone(r) with interconnected pores and their size between 100 and 500 μm, and it is composed of 20% by weight of HA and the rest is collagen type I. By infrared spectroscopy the functional groups of collagen type I (amide A - 3285, B - 2917, I - 1633, II - 1553 and III - 1239 cm−1) were identified. By thermal analysis it was determined that the phenomenon of denaturation of the collagen type I began in the range of 75-85 °C and burned above 200 °C
Disciplinas: Ingeniería,
Medicina
Palabras clave: Ingeniería de materiales,
Ingeniería biomédica,
Ingeniería de tejidos,
Biomateriales,
Matriz de colágeno,
Matriz ósea
Keyword: Engineering,
Medicine,
Materials engineering,
Biomedical engineering,
Tissue engineering,
Biomaterials,
Collagen matrix,
Bone matrix
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