| Revista: | Journal of applied research and technology |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000398843 |
| ISSN: | 1665-6423 |
| Autores: | Macías Martínez, B.I1 Cortés Hernández, D.A2 Zugasti Cruz, A1 Cruz Ortíz, B.R1 Múzquiz Ramos, E.M1 |
| Instituciones: | 1Universidad Autónoma de Coahuila, Facultad de Ciencias Químicas, Saltillo, Coahuila. México 2Instituto Politécnico Nacional, Centro de Investigación y de Estudios Avanzados, Ramos Arizpe, Coahuila. México |
| Año: | 2016 |
| Periodo: | Ago |
| Volumen: | 14 |
| Número: | 4 |
| Paginación: | 239-244 |
| País: | México |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Aplicado, descriptivo |
| Resumen en inglés | The present paper reports the heating ability and hemolysis test of magnetite nanoparticles (MNPs) for biomedical applications, obtained by a novel and easy co-precipitation method, in which it is not necessary the use of controlled atmospheres and high stirring rates. Different molar proportions of FeCl2:FeCl3 (2:1 and 3:2 respectively) were used and the obtained MNPs were analyzed by X-ray diffraction, vibrating sample magnetometry and transmission electron microscopy. The heating ability was evaluated under a magnetic field using a solid state induction heating equipment at two different frequencies (362 and 200 kHz). Additionally, a hemolysis test was performed according to the ASTM method. The obtained ferrites showed a particle size in the range of 8-12 nm and superparamagnetic behavior. The MNPs increased the temperature up to 43.1 °C in 5 min under a low magnetic field and showed non hemolytic effect up to 3 mg/ml. The MNPs obtained are highly potential materials for hyperthermia cancer treatment |
| Disciplinas: | Ingeniería, Medicina |
| Palabras clave: | Ingeniería de materiales, Ingeniería biomédica, Magnetita, Nanopartículas, Capacidad de calefacción, Prueba de hemólisis, Terapia hipertérmica |
| Keyword: | Engineering, Medicine, Materials engineering, Biomedical engineering, Magnetite, Nanoparticles, Heating ability, Hemolysis test, Hyperthermal therapy |
| Texto completo: | Texto completo (Ver HTML) |
