Bone and Dental DNA Damage Due to Extreme High-Temperature Exposure Through STR-CODIS, Y-STR and MtDNA Examinations
Título del documento: Bone and Dental DNA Damage Due to Extreme High-Temperature Exposure Through STR-CODIS, Y-STR and MtDNA Examinations
Revista: Gaceta médica de Caracas
Base de datos:
Número de sistema: 000596069
ISSN: 2739-0012
Autores: 1
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5
Instituciones: 1aDepartment of Forensic Medicine and Medicolegal, Faculty of Medicine, Universitas Airlangga, Surabaya, 60115, Indonesia. bForensic Science Program, Post Graduate School, Universitas Airlangga, Surabaya, 60115, Indonesia. c Human Genetic Study Group Institute of Tropical Disease, Universitas Airlangga, Surabaya, 60115, Indonesia,
2bForensic Science Program, Post Graduate School, Universitas Airlangga, Surabaya, 60115, Indonesia. c Human Genetic Study Group Institute of Tropical Disease, Universitas Airlangga, Surabaya, 60115, Indonesia,
3bForensic Science Program, Post Graduate School, Universitas Airlangga, Surabaya, 60115, Indonesia. dOral and Maxillofacial Pathology Faculty of Dental Medicine, Universitas Airlangga, Surabaya, 60115, Indonesia. e Doctoral Program of Medical Science Faculty of Medicine. Universitas Airlangga, Surabaya, 60115, Indonesia.,
4Human Genetic Study Group Institute of Tropical Disease, Universitas Airlangga, Surabaya, 60115, Indonesia,
5Universitas Anwar Medika, Sidoarjo, Indonesia,
Año:
Volumen: 132
Número: 2
País: Venezuela
Idioma: Español
Resumen en español Background: Forensic experts play an important role in forensic science. Identification through DNA analysis is an accurate and stable diagnostic tool. However, along with the development of DNA material examination, problems arise since DNA undergoes degradation, commonly known as degraded DNA. High-temperature exposure is one factor in DNA degradation. Bone and dental tissues are among the materials most resistant to this degradation. Bone and teeth are the most solid parts of the human body because they contain hydroxyapatite and extracellular matrices that protect DNA (nuclear DNA and mtDNA). DNA degradation due to high-temperature exposure on bone and dental DNA samples in forensic identification has been extensively unknown.
Palabras clave: High-temperature exposure,
STR-mini STR CODIS,
Y-STRs,
mtDNA,
bone and dental DNA,
mortality
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