A systematic review of the role of surfactants in bronchial asthma: Implications for pathogenesis and treatment of the disease
Título del documento: A systematic review of the role of surfactants in bronchial asthma: Implications for pathogenesis and treatment of the disease
Revista: Gaceta médica de Caracas
Base de datos:
Número de sistema: 000596059
ISSN: 2739-0012
Autores: 1
2
3
3
3
Instituciones: 1Osh State University, Pathology, Basic and Clinical Pharmacology Department, Osh, Kirguistán. Kirguistán
2Canakkale Onsekiz Mart University, Medical Pathology Department, Canakkale. Turquía
3Osh State University, Osh, Kirguistán. Kirguistán
Año:
Volumen: 132
Número: 1
País: Venezuela
Idioma: Inglés
Tipo de documento: Artículo
Resumen en español The study aims to examine existing literature and highlight the significance of surfactants as a factor in pathogenesis and a potential therapeutic target in bronchial asthma. A systematic search is conducted in Scopus, Web of Science, and PubMed/Medline, utilizing specific keywords related to surfactants and bronchial asthma. The findings demonstrate that surfactants, a unique mixture of lipids and proteins, play a crucial role in the mechanisms of innate and adaptive immunity in the lungs. They act as a mechanical barrier, modulate inflammatory responses, and interact with pathogens. Changes in surfactant composition and levels have been associated with various lung diseases, including bronchial asthma
Disciplinas: Medicina,
Medicina
Palabras clave: Neumología,
Farmacología
Keyword: Pneumology,
Pharmacology
Texto completo: Texto completo (Ver PDF) Texto completo (Ver HTML)