Endothelial wall thickness, cardiorespiratory fitness and inflammatory markers in obese and non-obese adolescents



Título del documento: Endothelial wall thickness, cardiorespiratory fitness and inflammatory markers in obese and non-obese adolescents
Revista: Brazilian journal of physical therapy
Base de datos: PERIÓDICA
Número de sistema: 000377281
ISSN: 1809-9246
Autores: 1
2
2
3
4
1
Instituciones: 1Universidade Federal do Parana, Departamento de Educacao Fisica, Curitiba, Parana. Brasil
2Universidade Estadual de Campinas, Faculdade de Educacao Fisica, Campinas, Sao Paulo. Brasil
3Universidade Paranaense, Departamento de Educacao Fisica, Francisco Beltrao, Parana. Brasil
4Universidade de Coimbra, Faculdade de Ciencias do Desporto e Educacao Fisica, Coimbra. Portugal
Año:
Periodo: Ene-Feb
Volumen: 18
Número: 1
Paginación: 47-55
País: Brasil
Idioma: Inglés
Tipo de documento: Estadística o encuesta
Enfoque: Analítico
Resumen en inglés Increased carotid intima-media thickness (c-IMT) is considered a marker of early-onset atherosclerosis and it has been found in obese children and adolescents, but the risk factors associated with this population remain to be elucidated. Objective: To compare and verify the relationship between c-IMT, metabolic profile, inflammatory markers, and cardiorespiratory fitness in obese and non-obese children and adolescents. Method: Thirty five obese subjects (19 boys) and 18 non-obese subjects (9 boys), aged 10-16 years, were included. Anthropometry, body composition, blood pressure, maximal oxygen consumption (VO2 max), and basal metabolic rate were evaluated. Serum glucose, insulin, homeostasis model assessment of insulin resistance (HOMA-IR), blood lipids, C-reactive protein (CRP), and adiponectin were assessed. c-IMT was measured by ultrasound. Results: The results showed that c-IMT, triglycerides, insulin, HOMA-IR, and CRP values were significantly higher in the obese group than in the non-obese group, and high-density lipoprotein cholesterol (HDL-c), adiponectin, and VO2 max values were significantly lower in the obese group than in the non-obese group. The c-IMT was directly correlated with body weight, waist circumference, % body fat, and HOMA-IR and inversely correlated with % free fat mass, HDL-c, and VO2 max. Conclusions: Our findings show that c-IMT correlates not only with body composition, lipids, insulin resistance, and inflammation but also with low VO2 max values in children and adolescents
Disciplinas: Medicina
Palabras clave: Metabolismo y nutrición,
Sistema cardiovascular,
Terapéutica y rehabilitación,
Obesidad,
Inflamación,
Aterosclerosis,
Adolescentes,
Terapia física,
Capacidad cardiorrespiratoria
Keyword: Medicine,
Cardiovascular system,
Metabolism and nutrition,
Therapeutics and rehabilitation,
Obesity,
Inflammation,
Atherosclerosis,
Adolescents,
Physical therapy,
Cardiorespiratory fitness
Texto completo: Texto completo (Ver PDF)