| Revista: | Brazilian Journal of Pharmaceutical Sciences |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000451215 |
| ISSN: | 1984-8250 |
| Autores: | Silva, Márcio Robert Mattos da1 Dysars, Letícia Pereira1 Santos, Elisabete Pereira dos1 Ricci-Junior, Eduardo1 |
| Instituciones: | 1Universidade Federal do Rio de Janeiro, Colegio de Farmacia, Rio de Janeiro. Brasil |
| Año: | 2020 |
| Volumen: | 56 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico, descriptivo |
| Resumen en inglés | At the hospital, the pharmacist is constantly challenged to prepare extemporaneous solutions from tablets, capsules or drug powder for patients unable to swallow, such as pediatric, elderly and patients that use nasoenteric and nasogastric tubes. The preparation of extemporaneous solutions from capsules, tablets and drug powder requires stability studies analysis. This article is a bibliographic review of preparation of extemporaneous oral liquid from solid oral dosage forms used in clinical practice. The selected articles contain all the information regarding manipulation techniques, pharmaceutical excipients, packaging, storage conditions and results of stability studies above 90% performed by HPLC analysis. In addition, a situational analysis of the strategies for the preparation of the extemporaneous solution was described to help the manipulator in the decision. The preparation of extemporaneous solution from solid oral dosage forms is based on information from official compendium or scientific literature, to ensure safe and effective manipulated medicine |
| Disciplinas: | Química, Medicina |
| Palabras clave: | Hospitales, Química farmacéutica, Preparaciones farmacéuticas, Líquidos orales, Formulación extemporánea |
| Keyword: | Hospitals, Medicinal chemistry, Pharmaceutical preparations, Oral liquids, Extemporaneous formulation |
| Texto completo: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
