| Revista: | Brazilian Journal of Pharmaceutical Sciences |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000451750 |
| ISSN: | 1984-8250 |
| Autores: | Santos, Andréa Timóteo dos1 Zardo, Andressa de Lima Godoi2 Kalva, Danielle Cristyane1 Maciel, Margarete Aparecida Salina1 |
| Instituciones: | 1Universidade Estadual de Ponta Grossa, Departamento de Analises Clinicas e Toxicologicas, Ponta Grossa, Parana. Brasil 2Casa de Repouso Sao Vicente de Paulo, Ponta Grossa, Parana. Brasil |
| Año: | 2022 |
| Volumen: | 58 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Experimental, aplicado |
| Resumen en inglés | Vitamin D is an immune modulator, in addition to being interrelated with calcium homeostasis and bone metabolism. Recent studies have associated vitamin D with inflammatory processes. C-reactive protein (CRP), platelet/lymphocyte ratio (PLR) and neutrophil/lymphocyte ratio (NLR) have been used to determine inflammation. There is no consensus on the use of these markers to determine an association between inflammation and vitamin D levels. The objective of this study was to evaluate the association between inflammatory markers and vitamin D in the elderly. A cross-sectional, descriptive study was performed based on the analysis of vitamin D, CRP (quantitative determination of C-Reactive Protein by the ultra-sensitive method) and blood count of institutionalized elderly. In this study, 64% showed vitamin D deficiency, with mean value of 22 ng/mL. In the vitamin D deficient group, the mean values found were: CRP 4.5 mg/L; NLR 2.35 and PLR 119. In the group without vitamin D deficiency the mean values were: CRP 4 mg/L; NLR 1.87 and PLR 111 without statistical difference between the values of the analyzed parameters. The results point to a predominant profile of vitamin D deficiency in the evaluated individuals. No association was found between vitamin D values and the inflammatory markers analyzed |
| Disciplinas: | Medicina |
| Palabras clave: | Geriatría, Inmunología, Inmunomoduladores, Marcadores inflamatorios, Vitamina D, Ancianos |
| Keyword: | Geriatrics, Immunology, Immunomodulators, Inflammatory markers, Vitamin D, Aged |
| Texto completo: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
