Evaluation of drug utilisation pattern and cost associated with diabetes mellitusType 2 management in Saudi Arabia



Título del documento: Evaluation of drug utilisation pattern and cost associated with diabetes mellitusType 2 management in Saudi Arabia
Revista: Brazilian Journal of Pharmaceutical Sciences
Base de datos: PERIÓDICA
Número de sistema: 000451872
ISSN: 1984-8250
Autores: 1
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2
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Instituciones: 1Mohammed Al-Mana College for Medical Sciences, Department of Pharmacy, Al Safa, Dammam. Saudi Arabia
2Mohammed Al-Mana College for Medical Sciences, Foundation Year Department, Al Safa, Dammam. Saudi Arabia
Año:
Volumen: 58
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Analítico, descriptivo
Resumen en inglés Diabetic mellitus is an emerging disease in Saudi Arabia. In this regard, a cross-sectional retrospective study was conducted to evaluate drug utilization pattern and the cost associated with non-insulin-dependent diabetes mellitus disease management in Saudi Arabia. Data retrieved from the electronic pharmacy records during the last one year were employed in this study. World Health Organization (WHO) Defined Daily Dose (DDD) method was employed to compute the daily price of each oral hypoglycaemic agent. The American Diabetes Association (ADA) guidelines and protocols were used to evaluate the level of adherence. A total of 17057 patients were enrolled in the study. Out of the 17057 patients enrolled in the study, 60.06 % (10246) were males and the rest females. In monotherapy, biguanides (metformin) were the most recommended and utilised drugs among 5673 patients (33.25%). The most commonly used drug combination was found to be sitagliptin+metformin (1754 units). The cost per unit dose was highest for liraglutide (A10BJ02) 258.32SR (68.79USD), and lowest for metformin (A10BA02) 0.49SR (0.13 USD). Metformin was the choice drug for the diabetes patients; biguanides (metformin) and DPP-4 (sitagliptins) were the most familiar established dose combination employed. Generic drugs should be used in order to reduce overall cost
Disciplinas: Medicina
Palabras clave: Endocrinología,
Farmacología,
Salud pública,
Diabetes mellitus tipo 2,
Hipoglucemiantes,
Patrones de consumo,
Análisis de costos
Keyword: Endocrinology,
Pharmacology,
Public health,
Diabetes mellitus type 2,
Hypoglycemic agents,
Consumption patterns,
Cost analysis
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