Revista: | Brazilian archives of biology and technology |
Base de datos: | PERIÓDICA |
Número de sistema: | 000372655 |
ISSN: | 1516-8913 |
Autores: | Renno, Ana Claudia Muniz1 Assis, Lívia1 Peres, Beatriz1 Rodrigues, Natalia Camargo2 Brunelli, Roberta de Matos2 Toma, Renata Luri1 Medalha, Carla Christina1 Ribeiro, Daniel Araki1 |
Instituciones: | 1Universidade Federal de Sao Paulo, Departamento de Biociencias, Sao Paulo. Brasil 2Universidade Federal de Sao Carlos, Centro de Ciencias Biologicas e da Saude, Sao Carlos, Sao Paulo. Brasil |
Año: | 2014 |
Periodo: | Ene-Feb |
Volumen: | 57 |
Número: | 1 |
Paginación: | 48-54 |
País: | Brasil |
Idioma: | Inglés |
Tipo de documento: | Artículo |
Enfoque: | Experimental |
Resumen en inglés | The main purpose of the present study was to investigate the effects of low-level laser therapy (LLLT) used in two different fluencies on injured skeletal muscle after cryolesion by means of histopathological analysis and immunohistochemistry for COX-2. A total of sixty male Wistar rats were randomly distributed into three groups: injured animals without any treatment; 808 nm laser treated group, at 10 J/cm² and 808 nm laser treated group, at 50 J/cm². Each group was divided into two different subgroups (n=10) on days 6 and 13 post-injury. The results showed that the animals irradiated with laser at 10 J/cm² or 50 J/cm² presented the areas with cell infiltrate and pointed out to minor and mild areas with destroyed zones compared with the control group. Also, a COX-2 downregulation was noticed in the groups exposed to laser at two fluences evaluated in this study. Significant statistically differences (p<0.05) were noticed to collagen deposition in the laser treated animals, with the fluence of 50 J/cm2 when compared to the other groups on day 13 post-surgery. Taken together, these results suggested that laser therapy could have positive effects on muscle repair in the rats after cryolesion |
Disciplinas: | Medicina, Biología |
Palabras clave: | Cirugía, Terapéutica y rehabilitación, Anatomía e histología, Terapia, Láser de bajo nivel, Ratas, Reparación muscular, COX-2 |
Keyword: | Medicine, Biology, Surgery, Therapeutics and rehabilitation, Anatomy and histology, Therapy, Low level laser, Rats, Muscle repair, COX-2 |
Texto completo: | Texto completo (Ver PDF) |