The effects of low level laser therapy on injured skeletal muscle



Título del documento: The effects of low level laser therapy on injured skeletal muscle
Revista: Brazilian archives of biology and technology
Base de datos: PERIÓDICA
Número de sistema: 000372655
ISSN: 1516-8913
Autores: 1
1
1
2
2
1
1
1
Instituciones: 1Universidade Federal de Sao Paulo, Departamento de Biociencias, Sao Paulo. Brasil
2Universidade Federal de Sao Carlos, Centro de Ciencias Biologicas e da Saude, Sao Carlos, Sao Paulo. Brasil
Año:
Periodo: Ene-Feb
Volumen: 57
Número: 1
Paginación: 48-54
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Experimental
Resumen en inglés The main purpose of the present study was to investigate the effects of low-level laser therapy (LLLT) used in two different fluencies on injured skeletal muscle after cryolesion by means of histopathological analysis and immunohistochemistry for COX-2. A total of sixty male Wistar rats were randomly distributed into three groups: injured animals without any treatment; 808 nm laser treated group, at 10 J/cm² and 808 nm laser treated group, at 50 J/cm². Each group was divided into two different subgroups (n=10) on days 6 and 13 post-injury. The results showed that the animals irradiated with laser at 10 J/cm² or 50 J/cm² presented the areas with cell infiltrate and pointed out to minor and mild areas with destroyed zones compared with the control group. Also, a COX-2 downregulation was noticed in the groups exposed to laser at two fluences evaluated in this study. Significant statistically differences (p<0.05) were noticed to collagen deposition in the laser treated animals, with the fluence of 50 J/cm2 when compared to the other groups on day 13 post-surgery. Taken together, these results suggested that laser therapy could have positive effects on muscle repair in the rats after cryolesion
Disciplinas: Medicina,
Biología
Palabras clave: Cirugía,
Terapéutica y rehabilitación,
Anatomía e histología,
Terapia,
Láser de bajo nivel,
Ratas,
Reparación muscular,
COX-2
Keyword: Medicine,
Biology,
Surgery,
Therapeutics and rehabilitation,
Anatomy and histology,
Therapy,
Low level laser,
Rats,
Muscle repair,
COX-2
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