| Revista: | Brazilian archives of biology and technology |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000374039 |
| ISSN: | 1516-8913 |
| Autores: | Silva, Camila Sloboda Pacheco da1 Kruger, Ernesto Renato2 Agottani, Jorge Victor Bacila2 Oliveira, Rubens Chaguri de3 Pereira, Sandro4 Penha, Tania Regina2 Ollhoff, Rudiger Daniel1 |
| Instituciones: | 1Pontificia Universidade Catolica do Parana, Escola de Ciencias Agrarias e Medicina Veterinaria, Curitiba, Parana. Brasil 2Instituto de Tecnologia do Parana, Laboratorio de Antigenos, Curitiba, Parana. Brasil 3Instituto de Tecnologia do Parana, Laboratorio de Vacina Antirabica, Curitiba, Parana. Brasil 4Instituto de Tecnologia do Parana, Laboratorio de Quimica, Curitiba, Parana. Brasil |
| Año: | 2013 |
| Periodo: | Nov-Dic |
| Volumen: | 56 |
| Número: | 6 |
| Paginación: | 928-931 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Experimental, aplicado |
| Resumen en inglés | The objective of this study was to formulate an anti-rabies oral vaccine from the cell culture vaccine PV TECPAR to elicit the production of antibodies against the rabies in mice. A vaccine was developed using 107.5 DL50/0.03 ml viral antigens homogenised in lanovaseline to facilitate oral administration. Mice were vaccinated two times for seroconversion. Sera of the vaccinated mice showed a higher level of antibody production than the control group. These results could be used to direct the development of an anti-rabies oral vaccine |
| Disciplinas: | Biología, Medicina |
| Palabras clave: | Inmunología, Farmacología, Rabia, Vacuna oral, Respuesta inmune, Ratones, ELISA |
| Keyword: | Biology, Medicine, Immunology, Pharmacology, Rabies, Oral vaccine, Immune response, Mice, ELISA |
| Texto completo: | Texto completo (Ver HTML) |
