Severe hepatitis induced by cyproterone acetate: role of corticosteroids. A case report



Título del documento: Severe hepatitis induced by cyproterone acetate: role of corticosteroids. A case report
Revista: Annals of hepatology
Base de datos: PERIÓDICA
Número de sistema: 000418130
ISSN: 1665-2681
Autores: 1
2
3
Instituciones: 1Universita Magna Graecia, Department of Health Sciences, Catanzaro, Calabria. Italia
2University of Novi Sad, Department of Pharmacy, Novi Sad. Serbia
3Hopital Jean Verdier, Service d’Hepato-Gastroenterologie, Bondy, Seine-Saint-Denis. Francia
Año:
Periodo: Feb
Volumen: 12
Número: 1
Paginación: 152-155
País: México
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Caso clínico, analítico
Resumen en inglés Cyproterone acetate (CPA) is an oral anti-androgen commonly used to treat advanced prostate cancer. A variety of hepatotoxic reactions has been reported with CPA. Here we describe a case of a male patient who developed severe drug-induced hepatotoxicity during the treatment with CPA. The case, presenting sub-acute hepatitis, was characterized by a rapid evolution of cirrhosis and a protracted activity during the period of a few months despite the treatment withdrawal and an apparent benefits of corticosteroids, suggesting their indication in life threatening cases
Disciplinas: Medicina
Palabras clave: Gastroenterología,
Farmacología,
Hepatotoxicidad,
Prednisona,
Budesonida,
Hepatitis crónica de interface,
Corticosteroides
Keyword: Gastroenterology,
Pharmacology,
Hepatotoxicity,
Prednisone,
Budesonide,
Interface hepatitis,
Corticosteroids
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