| Revista: | Annals of hepatology |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000418097 |
| ISSN: | 1665-2681 |
| Autores: | Silvestre, Odilson Marcos1 Bacal, Fernando1 Ramos, Danusa de Souza1 Furtado, Jose L1 Furtado, Meive1 Pugliese, Vincenzo1 Belleti, Elisangela1 Andraus, Wellington1 Carrilho, Flair Jose1 D’Albuquerque, Luiz Augusto Carneiro1 Farias, Alberto Queiroz1 |
| Instituciones: | 1Universidade de Sao Paulo, Faculdade de Medicina, Sao Paulo. Brasil |
| Año: | 2013 |
| Periodo: | Feb |
| Volumen: | 12 |
| Paginación: | 85-91 |
| País: | México |
| Idioma: | Inglés |
| Tipo de documento: | Estadística o encuesta |
| Enfoque: | Analítico |
| Resumen en inglés | The impact of end-stage liver disease (ESLD) in cardiac remodeling of patients with cirrhosis is unknown. Our aim was to correlate the severity of ESLD with morphologic and functional heart changes. Material and methods. 184 patients underwent a protocol providing data on the severity of ESLD and undergoing echocardiography to assess the diameters of the left atrium and right ventricle; the systolic and diastolic diameters of the left ventricle, interventricular septum, and posterior wall of the left ventricle; systolic pulmonary artery pressure; ejection fraction; and diastolic function. Severity of ESLD was assessed by the Model for End-Stage Liver Disease (MELD) score. Results. Left-atrial diameter (r = 0.323; IC 95% 0.190-0.455; p < 0.001), left-ventricular diastolic diameter (r = 0.177; IC 95% 0.033-0.320; p = 0.01) and systolic pulmonary artery pressure (r = 0.185; IC 95% 0.036-0.335; p = 0.02) significantly correlated with MELD score. Patients with MELD ≥ 16 had significantly higher left-atrial diameter and systolic pulmonary artery pressure, compared with patients with MELD scores < 16 points. Conclusions. Changes in cardiac structure and function correlate with the severity of ESLD |
| Disciplinas: | Medicina |
| Palabras clave: | Gastroenterología, Sistema cardiovascular, Cirrosis, Remodelación cardiaca, Trasplantes, Hígado, Cardiomiopatia cirrótica, Enfermedad hepática terminal |
| Keyword: | Gastroenterology, Cardiovascular system, Cirrhosis, Cardiac remodelling, Transplantation, Liver, Cirrhotic cardiomyopathy, End-stage liver disease |
| Texto completo: | Texto completo (Ver PDF) |
