| Revista: | Annals of hepatology |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000406047 |
| ISSN: | 1665-2681 |
| Autores: | Rios, Fernanda Ferreira1 Freitas, Luiz Antonio Rodrigues de1 Codes, Liana2 Santos-Junior, Genario Oliveira2 Schinoni, Maria Isabel1 Parana, Raymundo1 |
| Instituciones: | 1Universidade Federal da Bahia, Faculdade de Ciencias Medicas, Salvador, Bahia. Brasil 2Universidade Federal da Bahia, Hospital Universitario Prof. Edgard Santos, Salvador, Bahia. Brasil |
| Año: | 2016 |
| Periodo: | Nov-Dic |
| Volumen: | 15 |
| Número: | 6 |
| Paginación: | 932-938 |
| País: | México |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Caso clínico, analítico |
| Resumen en inglés | m. Non-cirrhotic idiopathic portal hypertension (NCIPH), also known as hepatoportal sclerosis (HPS) is a disease of uncertain etiology. However, many pathophysiological mechanisms has been postulated, including thrombophilia, chronic recurrent infections and exposure to drugs or toxins. In this context, it appears to be of multifactorial etiology or resulting from a portal vascular endothelium aggression. It is important to consider whether the use of dietary supplements and herbs can trigger or contribute to the occurance of HPS. We report a possible association of HPS with the consumption of herbal and / or dietary supplements. Material and methods. Material and methods. We Material and methods. describe two cases of HPS in patients without known etiology causes associated with this disease. Results. Results. Both patients were females who were Results. diagnosed with HPS following the consumption of Herbalife® products and putative anorexigenic agents in the herbal infusions. Image-based analysis and the assessment of the histopathological alterations found in the livers confirmed the diagnosis. The histopatological analysis of liver samples from both patients showed portal tracts enlarged by fibrosis with disappearance or reduction in the diameter of the portal vein branches. In many portal tracts, portal veins branches were replaced by aberrant thin-walled fendiforme vessels. The bile ducts and branches of the hepatic artery show normal aspects. Conclusion. Conclusion. Conclusion. After the exclusion of other etiologic factors and a comprehensive analysis of clinical history, consumption of Herbalife® products and anorexigenic agents was pointed-out as a puttative predisposing factor for the development of the disease |
| Disciplinas: | Medicina |
| Palabras clave: | Gastroenterología, Metabolismo y nutrición, Sistema cardiovascular, Fibrosis portal, Esclerosis hepatoportal, Suplementos nutricionales, Hepatotoxicidad |
| Keyword: | Medicine, Cardiovascular system, Gastroenterology, Metabolism and nutrition, Portal fibrosis, Hepatoportal sclerosis, Nutritional supplements, Hepatotoxicity |
| Texto completo: | Texto completo (Ver PDF) |
