Hepatic carcinosarcoma: clinicopathologic features and a review of the literature
Título del documento: Hepatic carcinosarcoma: clinicopathologic features and a review of the literature
Revista: Annals of hepatology
Base de datos: PERIÓDICA
Número de sistema: 000416172
ISSN: 1665-2681
Autores: 1
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Instituciones: 1Mackay Memorial Hospital, Taipei. Taiwán
Año:
Volumen: 12
Número: 3
Paginación: 495-500
País: México
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Caso clínico, analítico
Resumen en inglés Hepatic carcinosarcoma (HCS) is defined as a malignant tumor containing an intimate mixture of carcinomatous and sarcomatous elements. Here, we report the case of a 72-year-old man who developed HCS from an otherwise normal liver. The patient had no history of alcohol abuse or hepatitis B or C infection. An enhanced abdominal CT scan revealed a 9-cm heterogeneous tumor, with enhancement during the arterial phase and delayed wash-out in the latter phases. Also, a marked elevation in alpha-fetoprotein level (15,164 ng/mL; normal range, < 10 ng/mL) was noted. He underwent resection of liver segments V and VI under a pre-operative diagnosis of atypical hepatocellular carcinoma (HCC). The diagnosis of HCS was made based on thorough pathologic examination with a panel of immunohistochemical staining. Following surgery, the patient made an uneventful recovery, and at present, 16 months post-surgery, he remains well with no evidence of tumor recurrence. In conclusion, pre-operative diagnosis of HCS is difficult and radical resection in the early stage is encouraged to improve the prognosis of these patients
Disciplinas: Medicina
Palabras clave: Gastroenterología,
Oncología,
Cirugía,
Carcinoma hepatocelular,
Condrosarcoma,
Células pluripotenciales,
Carcinoma sarcomatoide
Keyword: Gastroenterology,
Oncology,
Surgery,
Hepatocellular carcinoma,
Chondrosarcoma,
Stem cells,
Sarcomatoid carcinoma
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