Feasibility and reliability of the FibroScan S2 (pediatric) probe compared with the M probe for liver stiffness measurement in small adults with chronic liver disease
Título del documento: Feasibility and reliability of the FibroScan S2 (pediatric) probe compared with the M probe for liver stiffness measurement in small adults with chronic liver disease
Revista: Annals of hepatology
Base de datos: PERIÓDICA
Número de sistema: 000418103
ISSN: 1665-2681
Autores: 1
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Instituciones: 1University of Calgary, Liver Unit, Division of Gastroenterology and Hepatology, Calgary, Alberta. Canadá
Año:
Periodo: Feb
Volumen: 12
Paginación: 100-107
País: México
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Experimental
Resumen en inglés The success of liver stiffness measurement (LSM) by transient elastography (TE, FibroScan) is influenced by anthropometric factors. In smaller adults, the M probe may fail due to narrow intercostal spaces and rib interference. We aimed to compare LSM using the FibroScan S2 (pediatric) probe with the M probe in small adults with chronic liver disease. Material and methods. In this prospective study, 41 liver disease patients and 18 controls with a thoracic perimeter ≤ 75 cm underwent LSM using the FibroScan M and S2 probes. TE failure was defined as no valid LSMs and unreliable examinations as < 10 valid LSMs, an interquartile range (IQR)/LSM > 30%, or success rate < 60%. Results. TE failure was not observed and reliability did not differ between the M and S2 probes (86% vs. 95%; P = 0.20). Liver stiffness measured using the M and S2 probes was highly correlated (ρ = 0.81; P < 0.0005) and median liver stiffness did not differ between probes (4.5 vs. 4.4 kPa; P = 0.10). However, in participants with a skin-capsular distance ≥ 15 mm, median liver stiffness was higher using the S2 probe (5.5 vs. 4.9 kPa; P = 0.008). When compared with validated liver stiffness cut-offs, the S2 probe would have overestimated the stage of fibrosis compared with the M probe in 10% of patients. Conclusions. The FibroScan S2 probe does not improve the feasibility of LSM in adults of smaller stature and may overestimate liver stiffness compared with the M probe. The FibroScan M probe should remain the preferred tool for LSM in small adults with chronic liver disease
Disciplinas: Medicina
Palabras clave: Gastroenterología,
Diagnóstico,
Biopsia,
Fibrosis hepática,
Hepatitis,
Diagnóstico no invasivo,
Fibroscan
Keyword: Gastroenterology,
Diagnosis,
Biopsy,
Hepatic fibrosis,
Hepatitis,
Non invasive diagnosis,
Fibroscan
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