Electrospun novel nanocomposite comprising polyurethane integrated with ayurveda amla oil for bone tissue engineering
Título del documento: Electrospun novel nanocomposite comprising polyurethane integrated with ayurveda amla oil for bone tissue engineering
Revista: Anais da Academia Brasileira de Ciencias
Base de datos: PERIÓDICA
Número de sistema: 000436187
ISSN: 0001-3765
Autores: 1
2
Instituciones: 1Ton Duc Thang University, Department for Management of Science and Technology Development, Ho Chi Minh City. Vietnam
2Universiti Teknologi Malaysia, School of Biomedical Engineering and Health Sciences, Skudai, Johor. Malasia
Año:
Volumen: 92
Número: 1
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Experimental, aplicado
Resumen en inglés Ayurveda oil contains numerous source of biological constituents which plays an important role in reducing the pain relief caused during bone fracture. The aim of the study is to fabricate the polyurethane (PU) scaffold for bone tissue engineering added with ayurveda amla oil using electrospinning technique. Scanning Electron Microscopy (SEM) analysis showed that the fabricated nanocomposites showed reduced fiber diameter (758 ± 185.46 nm) than the pristine PU (890 ± 116.91 nm). Fourier Infrared Analysis (FTIR) revealed the existence of amla oil in the PU matrix by hydrogen bond formation. The contact angle results revealed the decreased wettability (116° ± 1.528) of the prepared nanocomposites compared to the pure PU (100° ± 0.5774). The incorporation of amla oil into the PU matrix improved the surface roughness. Further, the coagulation assay indicated that the addition of amla oil into PU delayed the blood clotting times and exhibited less toxic to red blood cells. Hence, the fabricated nanocomposites showed enhanced physicochemical and better blood compatibility parameters which may serve as a potential candidate for bone tissue engineering
Disciplinas: Medicina,
Ingeniería
Palabras clave: Ingeniería de materiales,
Ingeniería biomédica,
Fracturas,
Ingeniería de tejidos,
Poliuretano,
Aceite de amalaki,
Biocompatibilidad,
Phyllanthus emblica
Keyword: Materials engineering,
Biomedical engineering,
Fractures,
Tissue engineering,
Polyurethane,
Amla oil,
Biocompatibility,
Phyllanthus emblica
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