Chemical composition and antibacterial activity of essential oils from Citrus aurantifolia leaves and fruit peel against oral pathogenic bacteria
Título del documento: Chemical composition and antibacterial activity of essential oils from Citrus aurantifolia leaves and fruit peel against oral pathogenic bacteria
Revista: Anais da Academia Brasileira de Ciencias
Base de datos: PERIÓDICA
Número de sistema: 000420096
ISSN: 0001-3765
Autores: 1
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2
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4
Instituciones: 1Instituto Federal de Educacao, Ciencia e Tecnologia Goiano, Rio Verde, Goias. Brasil
2Universidade de Franca, Centro de Pesquisa em Ciencias Exatas e Tecnologia, Franca, Sao Paulo. Brasil
3Universidade de Sao Paulo, Faculdade de Filosofia, Ciencias e Letras de Ribeirao Preto, Ribeirao Preto, Sao Paulo. Brasil
4Instituto Federal de Educacao, Ciencia e Tecnologia do Sul de Minas Gerais, Campus Pouso Alegre, Pouso Alegre, Minas Gerais. Brasil
Año:
Periodo: Jun
Volumen: 90
Número: 2
Paginación: 1285-1292
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Analítico
Resumen en inglés Tooth decay is a major public health problem which affects a large number of people in several countries. Even though more than 700 bacterial species have been detected in the oral cavity, Streptococcus and Lactobacillus stand out as the genera that cause tooth decay and other periodontal diseases. In this study, essential oils from Citrus aurantifolia leaves (CL-EO) and fruit peel (CP-EO) were obtained by hydrodistillation by a Clevenger-type apparatus whereas their chemical composition was analyzed by gas chromatography-flame ionization detector (GC-FID) and gas chromatography-mass spectrometry (GC-MS). Limonene (77.5 %), linalool (20.1 %), citronellal (14.5 %) and citronellol (14.2 %) were the main constituents found in the essential oils from C. aurantifolia leaves and fruit peel. Antibacterial activity of essential oils was evaluated in terms of its minimum inhibitory concentration (MIC) values by the broth microdilution method in 96-well microplates. Both CL-EO and CP-EO displayed some activity against all oral pathogens under investigation; MIC values ranged from 20 to 200 µg/mL. CLEO and CP-EO not only had promising activity against Streptococcus mutans (MIC = 20 µg/mL) and Lactobacillus casei (31.25 µg/mL), but also displayed antibacterial activity against all studied cariogenic bacteria. Efficacy of essential oils against S. mutans and L. casei is noteworthy and should be further investigated
Disciplinas: Química,
Medicina
Palabras clave: Química orgánica,
Fitoquímica,
Odontología,
Citrus aurantifolia,
Limoneno,
Bacterias cariogénicas,
Aceites esenciales,
Patógenos orales
Keyword: Organometallic chemistry,
Phytochemistry,
Dentistry,
Citrus aurantifolia,
Limonene,
Cariogenic bacteria,
Essential oils,
Oral pathogens
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