Adequacy of surgical margins, re-excision, and evaluation of factors associated with recurrence: a retrospective study of 769 basal cell carcinomas
Título del documento: Adequacy of surgical margins, re-excision, and evaluation of factors associated with recurrence: a retrospective study of 769 basal cell carcinomas
Revista: Anais brasileiros de dermatologia
Base de datos: PERIÓDICA
Número de sistema: 000460521
ISSN: 0365-0596
Autores: 1
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Instituciones: 1Trakya University, Faculty of Medicine, Edirne. Turquía
Año:
Periodo: Jul-Ago
Volumen: 98
Número: 4
Paginación: 449-459
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Aplicado, descriptivo
Resumen en inglés Achieving adequate surgical margins and preventing recurrence are important in the treatment of basal cell carcinoma (BCC). Objectives: The objectives of this study were to evaluate the adequacy of surgical margins and the re-excision rates in patients with primary BCC who underwent standard surgical treatment using our proposed algorithm and to define the risk factors in patients with recurrent BCC. Methods: The medical records of patients who were histopathologically diagnosed with BCC were reviewed. An algorithm created based on previous literature was used to determine the distribution of optimal surgical margins adequacy and re-excision rates. Results: Statistically significant differences were observed between the cases with and without recurrence in age at diagnosis (p = 0.004), tumor size (p = 0.023), tumor location in the H zone of the face (p = 0.005), and aggressive histopathological subtype (p = 0.000). When the tumors were evaluated for adequacy of deep and lateral surgical margins and re-excision rates, higher rates of adequate excision (457 cases, 68.0%) and re-excision (43 cases, 33.9%) were noted for tumors in the H or M zone. Study limitations: Inadequate follow-up of newly diagnosed patients in terms of recurrence and metastasis and the retrospective application of our proposed algorithm are the limitations of the present study. Conclusions: Our results showed that if BCC was detected at an early age and at an early stage, recurrence was lower. The H and M zones were the regions with the highest rates of optimal surgical outcomes
Disciplinas: Medicina
Palabras clave: Oncología,
Cirugía,
Carcinoma basocelular,
Resección quirúrgica,
Márgenes quirúrgicos,
Metástasis,
Recurrencia,
Factores de riesgo
Keyword: Oncology,
Surgery,
Basal cell carcinoma,
Surgical resection,
Surgical margins,
Metastasis,
Recurrence,
Risk factors
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