Anabolic-androgenic steroids cycle administration decreases anxious-like behavior but does not affect long-term memory acquisition in rats
Título del documento: Anabolic-androgenic steroids cycle administration decreases anxious-like behavior but does not affect long-term memory acquisition in rats
Revista: Acta scientiarum. Biological sciences
Base de datos: PERIÓDICA
Número de sistema: 000433603
ISSN: 1679-9283
Autores: 1
2
1
3
Instituciones: 1Universidade Federal do Pampa, Programa de Pos-graduacao em Ciencias Farmaceuticas, Uruguaiana, Rio Grande do Sul. Brasil
2Universidade Comunitaria da Regiao de Chapeco, Faculdade de Farmacia, Chapeco, Santa Catarina. Brasil
3Universidade Federal do Rio Grande do Sul, Faculdade de Farmacia, Porto Alegre, Rio Grande do Sul. Brasil
Año:
Volumen: 41
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Analítico, descriptivo
Resumen en inglés The steroid hormones are lipids in nature, which play crucial roles in several metabolic and behavioral pathways in mammals. Drug therapy uses sterol hormones for treating some disturbances linked with its deficiency; however, the illicit use of these hormones by amateur and elite athletes to enhance performance or body appearance may lead to several health issues. In this study we evaluated the anxious-like behavior and the long-term memory acquisition of male rats undergoing sedentary life-style or physical effort, with or without anabolic-androgenic steroids (ASC) treatment. The results showed a decrease in anxious-like behavioral levels in rats that received ASC treatment associated or not with physical effort, but this treatment did not affect the acquisition of long-term memory at the dose and experimental model assessed
Disciplinas: Biología,
Medicina
Palabras clave: Medicina experimental,
Química farmacéutica,
Psiquiatría,
Ejercicio físico,
Ansiedad,
Esteroides anabólicos,
Andrógenos,
Memoria,
Ratas
Keyword: Experimental medicine,
Medicinal chemistry,
Psychiatry,
Physical exercise,
Anxiety,
Memory,
Anabolic steroids,
Androgens,
Rats
Texto completo: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/45014/pdf