| Revista: | Veterinaria México OA |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000448382 |
| ISSN: | 2448-6760 |
| Autores: | Serrato López, Ana G1 Montesinos Montesinos, Juan J2 Anzaldúa Arce, Santiago R1 |
| Instituciones: | 1Universidad Nacional Autónoma de México, Facultad de Medicina Veterinaria y Zootecnia, Ciudad de México. México 2Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Ciudad de México. México |
| Año: | 2017 |
| Periodo: | Jul-Sep |
| Volumen: | 4 |
| Número: | 3 |
| Paginación: | 41-58 |
| País: | México |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Descriptivo |
| Resumen en inglés | Mesenchymal stem cells (MSCs) have been isolated from the endometrium of humans, mice, cows, pigs and ewes. Typically, these cells are detected in the deep regions of the endometrium, closer to the union with the myometrium. MSCs possess characteristics such as clonogenicity and multipotentiality since they can differentiate in vitro into adipogenic, chondrogenic and osteogenic lineages. These cells can be induced to differentiate in vitro not only into the mesodermal lineage but also into the endodermal and ectodermal lineages. Therefore, MSCs show a great regenerative capacity for various organs and tissues, including the endometrium. Some advantages of endometrial MSCs compared with other MSC sources are their immune modulating activity, their ease of obtainment, and the amount of sample that may be collected. The study of endometrial MSCs in domestic animals is a new and promising field because increasing our understanding of the physiology and biology of these cells may lead to a better understanding of the physiopathology of reproductive diseases, and the development of treatment methods for infertility problems. In other veterinary medicine fields, MSCs can be used for the treatment of autoimmune diseases, cardiac affections, musculoskeletal and articular lesions, muscle degeneration, type 1 diabetes, urinary tract diseases, neurodegenerative processes and tumours. Finally, MSCs are also an important clinical tool for tissue engineering and regenerative medicine. The aim of this review is to present an updated outlook of the knowledge regarding endometrial MSCs and their possible applications in veterinary medicine |
| Disciplinas: | Medicina veterinaria y zootecnia, Biología |
| Palabras clave: | Medicina veterinaria, Biología celular, Endometrio, Células madre mesenquimales, Investigación bibliográfica, Utero |
| Keyword: | Veterinary medicine, Cell biology, Bibliographic research, Uterus, Mesenchymal stem cells, Endometrium |
| Texto completo: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
