| Revista: | The brazilian journal of infectious diseases |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000290851 |
| ISSN: | 1413-8670 |
| Autors: | Neves, Denise Duprat1 Dias, Ricardo Marques Cunha, Antonio Jose Ledo Alves da2 Preza, Paulo Cesar Amorim |
| Institucions: | 1Universidade Federal do Rio de Janeiro, Hospital Universitario Gaffree e Guinle, Rio de Janeiro. Brasil 2Universidade Federal do Rio de Janeiro, Faculdade de Medicina, Rio de Janeiro. Brasil |
| Any: | 2004 |
| Període: | Ago |
| Volum: | 8 |
| Número: | 4 |
| Paginació: | 311-318 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Caso clínico |
| Resumen en inglés | In Rio de Janeiro, in almost half of the cases of pleural tuberculosis (PT) treatment begins without substantiation of diagnosis. We examined variables associated with this disease. We studied 215 consecutive patients; 104 had tuberculosis (TB) and 111 did not (NTB): 41 neoplasms, 29 transudates, 28 para-pneumonic and 13 other etiologies. Clinical and laboratory variables were assessed in a combined manner using likelihood ratios (LR) and Bayes' theorem to determine the probability of PT. Among the variables examined, adenosine deaminase (ADA) levels, lymphocyte cell percentage, protein and age were the best indicators for the diagnosis of PT. Association of ADA with any of the other variables led to a LR+ higher than 10 and a LR- lower than 0.1, indicating the presence or absence of PT, with an individual probability of more than 90% or of less than 10% considering that there was a 50% initial probability associated with the presence of PT. Since ADA is highly sensitive, we can practically exclude TB as the cause of effusion when there are low ADA values. However, to confirm the possibility of TB we recommend that other variables, such as prevalence of lymphocytes (higher than 90%), and high protein levels (more than 4g/dL); low age (less than 45 years) also should be considered |
| Disciplines | Medicina, Matemáticas |
| Paraules clau: | Diagnóstico, Neumología, Matemáticas aplicadas, Teorema de Bayes, Tuberculosis, Efusión pleural, Adenosina deaminasa |
| Keyword: | Medicine, Mathematics, Diagnosis, Pneumology, Applied mathematics, Bayes theorem, Tuberculosis, Pleural effusion, Adenosine deaminase |
| Text complet: | Texto completo (Ver HTML) |
