Revista: | Síndrome cardiometabólico |
Base de datos: | PERIÓDICA |
Número de sistema: | 000346507 |
ISSN: | 2244-7261 |
Autores: | Maiorana, C1 Duque, J 1 Pellino, M1 Tovar, S1 Lares, M1 Castillo, C1 Jiménez, A1 |
Instituciones: | 1Hospital Militar "Dr. Carlos Arvelo", Caracas, Distrito Federal. Venezuela |
Año: | 2011 |
Volumen: | 1 |
Número: | 2 |
Paginación: | 40-44 |
País: | Venezuela |
Idioma: | Español |
Tipo de documento: | Artículo |
Enfoque: | Aplicado, analítico |
Resumen en español | positiva, por lo que fueron llevados a laboratorio de hemodinamia resultando todos con enfermedad arterial coronaria. Conclusion: En pacientes con 2 o mas factores de riesgo para EAC, la PCRus podría ser considerada como factor predictor de ateroesclerosis coronario sobre todo si es relacionado con fibrinógeno > 350 mg/dl y LDLc > 100 mg/dl. La misma podría ser una herramienta útil en la escogencia de pacientes con alto riesgo para ser llevados a realización de CCG y de esta forma disminuir la morbi mortalidad cardiovascular, el número de eventos con Síndromes Coronarios agudos (SCA), y más aún instaurar e intensificar medidas de tratamiento en pacientes de riesgo antes de que aparezcan las complicaciones |
Resumen en inglés | The C-reactive protein (CRP) is an acute phase, highly sensitive phase general inflammation marker protein. In adults, the PCR, detected with ultra-sensitive techniques (PCRus), is associated with the traditional risk factors and its concentration predicts cardiovascular events. The objective of this study was to assess the usefulness of the protein C reactive (PCRus) as a tool for the diagnosis of Coronary Arterial Disease (CAD). A group of 37 patients from the Arterial Hypertension Unit of the military hospital Dr. Carlos Arvelo presenting 3 or more risk factors (RF) and no history of CDA were evaluated for glucose, total cholesterol, HDLc and LDLc, triglycerides, fibrinogen, and PCRus using a PATHFAT Analyzer. They were also subjected to transthoracic echocardiogram (TTE), two-dimensional stress test (ST) using a bruce protocol, and an echo stress with Dobutamine where the patients exhibiting positive results were further submitted to an angiography. Results: The patients had an average age of 60.54 ±5 years, 59.45% of which were male and 40.55% female. They exhibited the following characteristics: 100% hypertensive; 21.62% diabetics; 59.45% smokers; and 48.64% dyslipidemic. Further, 27.27% of the male population presented HDLc levels below 40 mg/ dl while 33.33% female population showed levels below 50 mg/dl; 75.67% of patients of both sexes presented LDLc > 100 m/dl; 40.54% were obese; 51.37% were sedentary; Fibrinogen > 350 mg/dl in 54.06%, corresponds to PCR us > 1 mg/l of 75.67%. Those who had PCRus > 2.6 mg/l represented 40.55% of the total target group (15 patients), the latter being associated with a cardiovascular risk increase of 2. Ten patients exhibited a LDLc > 100 mg/dl with Fibrinogen > 350 mg/dl and PCR us > 2.6 mg/l, 60% of these patients presented evidence of induced ischemia, and consequently were submitted to hemodynamia and all were suffering from coronary artery disease. Conclusion: In patients with 2 or more risk factors for.. |
Disciplinas: | Medicina |
Palabras clave: | Diagnóstico, Metabolismo y nutrición, Sistema cardiovascular, Aterosclerosis, Proteína C reactiva, Factores de riesgo, Enfermedad coronaria |
Keyword: | Medicine, Cardiovascular system, Diagnosis, Metabolism and nutrition, Atherosclerosis, C reactive protein, Risk factors, Coronary artery disease |
Texto completo: | Texto completo (Ver PDF) |