Evaluation of the impact of parameters on the gamma index for breast cancer treatments



Título del documento: Evaluation of the impact of parameters on the gamma index for breast cancer treatments
Revista: Revista mexicana de física
Base de datos: PERIÓDICA
Número de sistema: 000447369
ISSN: 0035-001X
Autors: 1
1
2
3
Institucions: 1Instituto Nacional de Enfermedades Neoplásicas, Lima. Perú
2Universidad Nacional de Ingeniería, Lima. Perú
3Universidad Nacional Mayor de San Marcos, Lima. Perú
Any:
Període: Nov-Dic
Volum: 67
Número: 6
País: México
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Analítico, teórico
Resumen en inglés Volumetric modulated arc radiotherapy treatments (VMAT) can achieve highly conformed dose distributions however, due to the complexity of the technique, there may have differences between the planned and administered dose distributions, generated by the precision in the dose calculation of the treatment planning system (TPS) or by the errors associated with it. One way to quantify the difference between both dose distributions is by using the gamma index; however, there is no accord regarding the parameters that should be used in its analysis. On the other hand, this gamma index may depend on the pathology and the area to be treated. For this reason, the present work aims to evaluate different parameters of the analysis of the gamma index for breast cancer treatments; these are local and global normalization, the analysis criteria (1%/1 mm, 2%/2 mm, 3%/2 mm, 2%/3 mm, 3%/3 mm and 5%/3 mm), and the low dose threshold (LDT) of 5% and 10%. For this, 30 treatment plans performed with VMAT technique in a 6 MV Infinity linear accelerator (Elekta, Stockholm, Sweden) were analyzed, calculated with the TPS Monaco V.5.11.03 (Elekta, Stockholm, Sweden) and measured with the Octavius 4D system (PTW, Freiburg, Germany). The results of the analysis of the global gamma index were of a gamma passing rate (%GP) greater than 95% for analysis criteria of 3%/3 mm and 5%/3 mm; however, for these same parameters in the local gamma index analysis, the results are 85.8% and 91.1% respectively. In addition, from the LDT evaluation, it is observed that there is a mean increase of %GP for the local gamma index analysis and a mean decrease of %GP for the global gamma index analysis, for the LDT from 5% to 10%. On the other hand, the standard deviation is lower in the global gamma index; analysis than in the local one, and it decreases when the analysis criteria are less strict. It is concluded that there is not a great difference in choosing the LDT of 5% or 10%. When the gamma analy
Disciplines Física y astronomía
Paraules clau: Pacientes,
Indice Gamma,
VMAT,
Umbral de dosis inferior,
Criterio de análisis,
Control de calidad
Keyword: Patients,
Gamma index,
VMAT,
Lower dose threshold,
Analysis criteria,
Quality control
Text complet: Texto completo (Ver HTML) Texto completo (Ver PDF)