Endothelial cell viability comparing Eusol-C vs Optisol-GS as corneal preservation medium
Título del documento: Endothelial cell viability comparing Eusol-C vs Optisol-GS as corneal preservation medium
Revista: Revista médica del Hospital General de México
Base de datos:
Número de sistema: 000602850
ISSN: 0185-1063
Autores: 1
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Instituciones: 1Hospital General de México, Departamento de Cirugía de Córnea y Refractiva, Ciudad de México. México
Año:
Periodo: Oct-Dic
Volumen: 86
Número: 4
Paginación: 129-134
País: México
Idioma: Inglés
Tipo de documento: Artículo
Resumen en inglés Introduction: Optisol-GS is the most widely used corneal preservation medium worldwide, there is little evidence to compare it against Eusol-C as a corneal preservation medium. Objectives: To evaluate the viability of endothelial cells between two different corneal preservation media. Materials and Methods: It is a prospective, longitudinal, and comparative study, which was carried out in the eye bank of Hospital General de México "Dr. Eduardo Liceaga", from where the corneas of suitable donors were collected, the right cornea was preserved in Optisol-GS and the left in Eusol-C. Two evaluations were carried out on day 1 and 5. Endothelial cell density, coefficient of cell variation and hexagonality were analysed. Results: The decrease in endothelial cells on day 5 after collection of the corneoscleral tissue was 8.149% in the corneas stored in Optisol-GS and 7.614% in Eusol-C p=0.006. Cell variation increased 1.634% in Optisol-GS and 8.942% in Eusol-C p=0.948. Cell hexagonality decreased 6.988% in Optisol-GS and 9.480% in Eusol-C p=0.936. Conclusions: No superiority was found when comparing these two media, which shows that Eusol-C is as effective as Optisol-GS for corneal preservation for at least five days.
Disciplinas: Medicina,
Biología,
Medicina
Palabras clave: Oftalmología,
Biología celular,
Cirugía
Keyword: Ophthalmology,
Cell biology,
Surgery
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