Reporte de un caso de Síndrome de Guillain Barré post vacuna Coronavac: ¿rol causal o asociación temporal?



Título del documento: Reporte de un caso de Síndrome de Guillain Barré post vacuna Coronavac: ¿rol causal o asociación temporal?
Revista: Revista médica de Chile
Base de datos: PERIÓDICA
Número de sistema: 000448943
ISSN: 0034-9887
Autors: 1
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Institucions: 1Hospital del Trabajador de Santiago, Servicio de Neurología, Santiago de Chile. Chile
Any:
Període: Ene
Volum: 150
Número: 1
Paginació: 125-130
País: Chile
Idioma: Español
Tipo de documento: Artículo
Enfoque: Caso clínico, descriptivo
Resumen en inglés We report a 50-year-old woman with a history of celiac disease, who presented with lumbar pain and progressive flaccid tetraparesis 48 hours after the inoculation of the first dose of CoronaVac inactivated SARS-CoV-2 vaccine. CSF was normal and electrodiagnostic studies showed an axonal motor polyneuropathy. No other triggers were identified, and other etiologies were ruled out. The presentation was compatible with the AMAN (Acute Motor Axonal Neuropathy) subtype of GBS, and intravenous immunoglobulin halted the progression of symptoms. Intensive neurorehabilitation was performed. The patient was discharged five weeks after admission, walking with poles and climbing stairs with minimal assistance. To date no cases of inactivated SARSCoV-2 vaccine related GBS have been reported. Thus, description of its clinical presentation is relevant. We discuss the current evidence relating GBS with vaccines, highlighting that vaccine associated GBS is a controversial entity and causality must be interpreted cautiously given the actual COVID-19 pandemic context
Disciplines Medicina
Paraules clau: Virus,
Inmunología,
COVID-19,
Vacunas,
Efectos adversos,
Síndrome de Guillain-Barré
Keyword: Virus,
Immunology,
COVID-19,
Vaccines,
Adverse effects,
Guillain-Barre syndrome
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