| Revista: | Revista médica de Chile |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000341950 |
| ISSN: | 0034-9887 |
| Autors: | Acle, Santiago1 Roca, Federico1 Vacarezza, Mariela1 Alvarez Rocha, Alfredo1 |
| Institucions: | 1Universidad de la República, Facultad de Medicina, Montevideo. Uruguay |
| Any: | 2011 |
| Període: | Dic |
| Volum: | 139 |
| Número: | 12 |
| Paginació: | 1597-1600 |
| País: | Chile |
| Idioma: | Español |
| Tipo de documento: | Artículo |
| Enfoque: | Caso clínico |
| Resumen en inglés | Ergotism is a complication of the acute intoxication or chronic abuse of ergot derivatives. It may be manifested by a vasomotor syndrome with peripheral vascular disease frequently involving extremities. We report three patients infected with human immunodeficiency virus (HIV), in antiretroviral treatment (ART) that included a protease inhibitor as ritonavir, and had received self-medicated ergotamine. They developed symptoms of peripheral vascular disease and the physical examination showed no arterial pulses in the affected vessels. Arterial Doppler confirmed signs of diffuse arterial spasm in all of them. An arteriography was performed to the second patient and it showed obliteration of the distal sector of the ulnar and radial arteries. Ergotism secondary to ergotamine-ritonavir association was diagnosed. Patients were treated discontinuing the administration of involved drugs, arterial vasodilators and prophylactic anticoagulation, with marked improvement of symptoms |
| Disciplines | Medicina |
| Paraules clau: | Farmacología, Ergotamina, Ritonavir, Ergotismo, Sindrome vasomotor, Enfermedad vascular periférica |
| Keyword: | Medicine, Pharmacology, Ergotamine, Ritonavir, Ergotism, Vasomotor syndrome, Peripheric vascular disease |
| Text complet: | Texto completo (Ver HTML) |
