| Revista: | Revista do Instituto de Medicina Tropical de Sao Paulo |
| Base de datos: | |
| Número de sistema: | 000547849 |
| ISSN: | 0036-4665 |
| Autors: | Carvalho Silva, Reyllane1 Ribeiro da Silva, Rosa Cristina1 Cruz, Léo Nava Piorsky Dominici2 Oliveira, Maxcilene da Silva de3 Amoedo, Pedro Marinho4 Rebêlo, José Manuel Macário5 Guimarães e Silva, Antonia Suely1 Pinheiro, Valéria Cristina Soares1 |
| Institucions: | 1Universidade Estadual do Maranhão, Programa de Pós-Graduação em Biodiversidade Ambiente e Saúde, Caxias, Maranhão. Brasil 2Fundação Oswaldo Cruz, Instituto Oswaldo Cruz, Rio de Janeiro. Brasil 3Universidade Estadual do Maranhão, Programa de Pós-Graduação em Biodiversidade e Biotecnologia, Caxias, Maranhão. Brasil 4Universidade Federal do Amazonas, Unidade Acadêmica de Parintins, Parintins, Amazonas. Brasil 5Universidade Federal do Maranhão, Laboratório de Entomologia e Vetores, São Luís. Brasil |
| Any: | 2022 |
| Volum: | 64 |
| País: | Brasil |
| Idioma: | Inglés |
| Resumen en inglés | Leishmaniasis is a serious public health concern in the Northeastern region of Brazil, where the sand fly fauna is well studied, although few species have been identified as competent vectors. The detection of Leishmania spp. parasites in wild-caught sand flies could help sanitary authorities draw strategies to avoid the transmission of the parasites and, therefore, the incidence of leishmaniases. We detected Leishmania DNA in wild-caught sand flies and correlated that data with aspects of sand fly ecology in the Caxias municipality, Maranhao State, Brazil. The sand flies were sampled in the peridomicile (open areas in the vicinity of human residences) and intradomicile (inside the residences) from July/2019 to March/2020. Leishmania DNA was detected in females, targeting a fragment of the Internal Transcribed Spacer (ITS1) from ribosomal DNA. Among the fourteen species of sand flies identified, five (Lutzomyia longipalpis, Nyssomyia whitmani, Evandromyia evandroi, Micropygomyia trinidadensis, and Micropygomyia quinquefer) harbored DNA of Leishmania (Leishmania) amazonensis. The most abundant species in rural (Ny. whitmani: 35.2% and Ev. evandroi: 32.4%) and urban areas (Lu. longipalpis: 89.8%) are the permissive vectors of L. (L.) amazonensis, especially Ny. whitmani, a known vector of causative agents of cutaneous leishmaniasis. Although Lu. longipalpis is the vector of L. (L.) infantum, which was not detected in this study, its permissiveness for the transmission of L. (L.) amazonensis has been reported. We suspect that visceral leishmaniasis and cutaneous leishmaniasis are caused by L. (L.) amazonensis, and the transmission may be occurring through Lu. longipalpis, at least in the urban area. |
| Keyword: | Phlebotomines, Infectious parasitic diseases, Parasites, Molecular biology |
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