| Revista: | Revista da Sociedade Brasileira de Medicina Tropical |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000281924 |
| ISSN: | 0037-8682 |
| Autors: | Santos, Vitorino Modesto dos1 Cunha, Selma Freire de Carvalho da Teixeira, Vicente de Paula Antunes Monteiro, Jaqueline Pontes Santos, Jenner Arruda Modesto dos Santos, Taciana Arruda Modesto dos Santos, Lister Arruda Modesto dos Cunha, Daniel Ferreira da1 |
| Institucions: | 1Faculdade de Medicina do Triangulo Mineiro, Departamento de Clinica Medica, Uberaba, Minas Gerais. Brasil |
| Any: | 1999 |
| Període: | Sep-Oct |
| Volum: | 32 |
| Número: | 5 |
| Paginació: | 489-496 |
| País: | Brasil |
| Idioma: | Portugués |
| Tipo de documento: | Artículo |
| Enfoque: | Caso clínico, analítico |
| Resumen en inglés | Medical records of≥ 40 years old female seen at University Hospital from June/93 to July/95 were submitted to a cross-sectional study. According to Chagas' disease tests, patients were divided into chagasic (n = 362) and controls (n = 285). Diabetes mellitus was defined on the basis of two fasting blood glucose levels ³ 140mg/dl and hyperglycemia as fasting blood glucose > 110mg/dl. Chagasic patients were divided into groups with the cardiac form of the disease (n = 179), with megas (n = 58), and asymptomatic (n = 125). Groups were compared by the c2 test, analysis of variance, Student's "t" test, and Kruskal-Wallis and Mann-Whitney tests. A significant difference was assumed when p < 0.05. Chagasic and control groups were matched for age, white color and body mass index. Diabetes mellitus was more prevalent in patients with the cardiac form of Chagas' disease than in controls, or patients with the megas or the asymptomatic form (15.1%, 7.4%, 7.4%, and 5.6%, respectively); the same was observed for hyperglycemia (37.4%, 26.7%, 25.9%, 27.2%), in agreement with the hypothesis that the reduced parasympathetic activity caused by Trypanosoma cruzi leads to relative sympathetic hyperactivity |
| Resumen en portugués | Estudo retrospectivo de 647 mulheres com idade ≥40 anos, atendidas no Hospital-Escola da FMTM, Uberaba-MG. As três sorologias para a doença de Chagas foram negativas nas controles (n = 285) e positivas nas chagásicas (n = 362), que foram classificadas nas formas indeterminada (n = 125), megas (n = 58) e cardíaca (n = 179). Diabetes mellitus foi definido por duas glicemias em jejum ³ 140mg/dl e hiperglicemia por glicemia em jejum > 110mg/dl. Os grupos foram comparados pelos testes do c2, análise de variância, "t" de Student, Kruskal-Wallis e Mann-Whitney, considerando-se significativo p < 0,05. chagásicas e controles estavam pareadas quanto à idade, o índice de massa corporal e a cor. Diabetes mellitus foi mais freqüente na forma cardíaca (15,1%), comparada com as controles (7,4%), megas (7,4%) e assintomáticas (5,6%), o mesmo ocorrendo com a hiperglicemia (37,4%, 26,7%, 25,9% e 27,2%, respectivamente), achados que estão de acordo com possível desnervação parassimpática causada pelo Trypanosoma cruzi e conseqüente predomínio da atividade simpática |
| Disciplines | Biología, Medicina |
| Paraules clau: | Parasitología, Protozoarios, Endocrinología, Neurología, Enfermedad de Chagas, Disfunción autónoma, Hiperglicemia, Diabetes mellitus |
| Keyword: | Biology, Medicine, Parasitology, Protozoa, Endocrinology, Neurology, Chagas disease, Autonomic dysfunction, Hyperglycemia, Diabetes mellitus |
| Text complet: | Texto completo (Ver HTML) |
