| Revista: | Quimica nova |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000313167 |
| ISSN: | 0100-4042 |
| Autors: | Nakagaki, Shirley1 Friedermann, Geraldo Roberto Caiut, Jose Mauricio Almeida |
| Institucions: | 1Universidade Federal do Parana, Departamento de Quimica, Curitiba, Parana. Brasil |
| Any: | 2006 |
| Període: | Sep |
| Volum: | 29 |
| Número: | 5 |
| Paginació: | 1003-1008 |
| País: | Brasil |
| Idioma: | Portugués |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico, descriptivo |
| Resumen en inglés | This review presents studies on methyl coenzyme M reductase, the biological system Factor 430 (F430) and the use of nickel(II) complexes as structural and functional models. The ability of F430 and nickel(II) macrocycle complexes to mediate the reductive dehalogenation of cyclohexyl halogens and the CH3-S bond cleavage of methyl CoM (by sodium borohydride and some intermediate species) proposed for the catalytic cycle of the biological system F430 was reviewed. The importance of the structure of the nickel complexes and the condition of the catalytic reduction reaction are also discussed |
| Disciplines | Química |
| Paraules clau: | Bioquímica, Metil-coenzima M reductasa, Complejos de níquel, Modelo funcional |
| Keyword: | Chemistry, Biochemistry, Methyl-coenzyme M reductase, Nickel complexes, Functional model |
| Text complet: | Texto completo (Ver HTML) |
