| Revista: | Materials research |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000312968 |
| ISSN: | 1516-1439 |
| Autores: | Costa, Vilma Conceicao1 Costa, Hermes Souza Vasconcelos, Wander Luiz Pereira, Marivalda de Magalhaes Oréfice, Rodrigo Lambert Mansur, Herman Sander |
| Instituciones: | 1Universidade Federal de Minas Gerais, Departamento de Engenharia Metalurgica e de Materiais, Belo Horizonte, Minas Gerais. Brasil |
| Año: | 2007 |
| Periodo: | Ene-Mar |
| Volumen: | 10 |
| Número: | 1 |
| Paginación: | 21-26 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Nota breve o noticia |
| Enfoque: | Experimental |
| Resumen en inglés | Tissue engineering has evolved from the use of biomaterials for bone substitution that fulfill the clinical demands of biocompatibility, biodegradability, non-immunogeneity, structural strength and porosity. Porous scaffolds have been developed in many forms and materials, but few reached the need of adequate physical, biological and mechanical properties. In the present paper we report the preparation of hybrid porous polyvinyl alcohol (PVA)/bioactive glass through the sol-gel route, using partially and fully hydrolyzed polyvinyl alcohol, and perform structural characterization. Hybrids containing PVA and bioactive glass with composition 58SiO2-33CaO-9P2O5 were synthesized by foaming a mixture of polymer solution and bioactive glass sol-gel precursor solution. Sol-gel solution was prepared from mixing tetraethoxysilane (TEOS), triethylphosphate (TEP), and calcium chloride as chemical precursors. The hybrid composites obtained after aging and drying at low temperature were chemically and morphologically characterized through infrared spectroscopy and scanning electron microscopy. The degree of hydrolysis of PVA, concentration of PVA solution and different PVA-bioglass composition ratios affect the synthesis procedure. Synthesis parameters must be very well combined in order to allow foaming and gelation. The hybrid scaffolds obtained exhibited macroporous structure with pore size varying from 50 to 600 µm |
| Disciplinas: | Ingeniería, Medicina, Química |
| Palabras clave: | Ingeniería de materiales, Traumatología y ortopedia, Química de polímeros, Biomateriales, Biocerámica, Sol-gel, Histología |
| Keyword: | Engineering, Medicine, Chemistry, Materials engineering, Traumatology and orthopedics, Polymer chemistry, Biomaterials, Bioceramics, Sol-gel, Histology |
| Texto completo: | Texto completo (Ver HTML) |
