Revista: | Journal of the Mexican Federation of Radiology and Imaging |
Base de datos: | |
Número de sistema: | 000606811 |
ISSN: | 2696-8444 |
Autores: | Ramos Sánchez, Rebeca de J1 Carrillo Mezo, Roger A1 Martínez López, Yazmín2 Flores Rivera, José2 Ramírez Flores, Héctor1 |
Instituciones: | 1Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, Departamento de Neuroimagen, Ciudad de México. México 2Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, Departamento de Neuroinmunología, Ciudad de México. México |
Año: | 2024 |
Periodo: | Ene-Mar |
Volumen: | 3 |
Número: | 1 |
Paginación: | 27-35 |
País: | México |
Idioma: | Inglés |
Tipo de documento: | Artículo |
Resumen en inglés | Introduction: Paramagnetic rim lesions (PRLs) in multiple sclerosis (MS) patients have been described with different magnetic field strengths in magnetic resonance imaging (MRI). This study aimed to identify the characteristics of PRLs in magnitude and filtered phase susceptibility weighted imaging (SWI/SWAN) in 1.5T and 3.0T MRI in Mexican patients with MS and to determine interobserver agreement. Materials and methods: This retrospective cross-sectional study assessed adults with MS who underwent 1.5T or 3.0T MRI with SWI/SWAN. The variables, sex, age, MS duration, annualized relapse rate, the severity of current disability determined by the Expanded Disability Status Scale (EDSS), the MS clinical phenotype, and the presence, number, location, and volume of PRLs were assessed. Cohens kappa was used to calculate interobserver agreement. Results: A total of 76 patients with MS were included. At least one PRL was found in 60 (78.9%). A total of 375 PRLs were detected: 233 in 42 (76.4%) of 55 patients with 1.5T MRI with a mean of 5.54 per patient and 142 PRLs in 18 (85.7%) of 21 patients with 3.0T MRI with a mean of 7.9 per patient. The most common location was periventricular (n = 49, 81.7%). A significant association was found between PRLs and younger patients (p = 0.017), a shorter disease evolution (p = 0.010), an annualized relapse rate (p = 0.030), and a higher volume of white matter lesions (p = 0.035). Interobserver agreement was good ( = 0.709, 95% CI, 0.7020.716). Conclusion: This study is the first in Mexico that characterizes PRLs with 1.5T and 3.0T MRI magnetic fields in patients with MS with good interobserver agreement. |
Disciplinas: | Medicina, Medicina |
Palabras clave: | Neurología, Diagnóstico |
Keyword: | Neurology, Diagnosis |
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