Can the absence of breast arterial calcifications on mammography predict the absence of coronary artery calcifications?



Título del documento: Can the absence of breast arterial calcifications on mammography predict the absence of coronary artery calcifications?
Revista: Journal of the Mexican Federation of Radiology and Imaging
Base de datos:
Número de sistema: 000606819
ISSN: 2696-8444
Autores: 1
2
1
1
3
4
1
Instituciones: 1Hospital Zambrano Hellion TEC-Salud, Centro de Diagnóstico por Imagenología de Mama, Monterrey, Nuevo León. México
2Instituto Tecnológico y de Estudios Superiores de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey, Nuevo León. México
3Hospital San José Tec Salud, Departamento de Radiología e Imagen, Monterrey, Nuevo León. México
4Hospital Zambrano Hellion TEC-Salud, Departamento de Imagenología Cardiaca, Monterrey, Nuevo León. México
Año:
Periodo: Ene-Mar
Volumen: 3
Número: 3
Paginación: 150-161
País: México
Idioma: Inglés
Tipo de documento: Artículo
Resumen en inglés Introduction: It has been suggested that breast arterial calcifications (BAC) on mammography predict coronary artery calcifications (CAC). However, it has been insufficiently addressed to rule out the presence of CAC. This study aimed to determine whether the absence of BAC on mammography is associated with the absence of CAC using the coronary computed tomography (CT) calcium score in women. Material and methods: This retrospective cross-sectional study included asymptomatic women who underwent digital screening mammography and coronary CT calcium score testing. BAC score was grouped into three categories: absence, intermediate, and significant. The Agatston score was used to quantify CAC. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of BAC were calculated to predict CAC. Results: We included 611 asymptomatic women with a mean age of 51.3 ± 8.37 years. The prevalence of BAC was 9.1% (n = 56), and CAC was 13.4% (n = 82). There was a significant association between the absence of BAC and no CAC (n = 501, 93.5%; p < 0.001). BAC diagnostic performance was stratified by age. In women under 60 years (n = 525), specificity was 94.6% (95% CI, 91.4-95.6), and the NPV 92.6% (95% CI, 91.4-95.6) for the absence of BAC in predicting no CAC. In women aged 60 years (n = 86), specificity was 82.6% (95% CI, 68.5-92.1), and the NPV was 60.3% (95% CI, 53.6-66.6). The sensitivity (14.2%, 95% CI, 16.1-35.05) and PPV (18.7%, 95% CI, 25.3-51.02) in women under 60 years were lower than in women 60 years with a sensitivity of 37.5% (95% CI, 22.7-54.2) and a PPV of 65.2% (95% CI, 47.0-79.8). Conclusion: The absence of BAC in screening mammography has the highest diagnostic performance for predicting the absence of CAC, especially in women under 60 years of age.
Disciplinas: Medicina,
Medicina
Palabras clave: Sistema cardiovascular,
Diagnóstico
Keyword: Cardiovascular system,
Diagnosis
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