| Revista: | International braz j urol |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000296636 |
| ISSN: | 1677-5538 |
| Autores: | Eggener, Scott1 Kim, Samuel C User, Herbert M Pazona, Joseph Nadler, Robert B |
| Instituciones: | 1Northwestern University, Department of Urology, Chicago, Illinois. Estados Unidos de América |
| Año: | 2004 |
| Periodo: | Ene-Feb |
| Volumen: | 30 |
| Número: | 1 |
| Paginación: | 29-31 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Caso clínico, descriptivo |
| Resumen en inglés | OBJECTIVE: Topiramate is a sulfamate-substituted monosaccharide anticonvulsant used as adjunctive therapy for intractable refractory seizures. It is report a case of topiramate-induced urolithiasis. CASE REPORT: A 35-year-old man presented with acute, right-sided, colicky flank pain. He denied hematuria or dysuria. He was in use of phenytoin, risperidone, phenobarbital, and topiramate. The total daily dose of topiramate was 375 mg. A CT scan showed a 7 x 1 mm curvilinear density at the right ureterovesical junction with proximal hydrouretronephrosis. He was managed with rigid ureteroscopic stone extraction and the calculus metabolic analysis revealed the stone was composed of carbonate apatite (70%), calcium oxalate dihydrate (20%), and calcium oxalate monohydrate (10%). COMMENTS: The present case typifies many features of topiramate-induced urolithiasis. Those who care for patients with urinary stone disease should be aware of this association |
| Disciplinas: | Medicina |
| Palabras clave: | Cirugía, Farmacología, Metabolismo y nutrición, Urolitiasis, Acidos, Anticonvulsivos, Efectos adversos |
| Keyword: | Medicine, Metabolism and nutrition, Pharmacology, Surgery, Urolithiasis, Acids, Anticonvulsants, Adverse effects |
| Texto completo: | Texto completo (Ver HTML) |
