Upper urinary tract stone compositions: the role of age and gender



Título del documento: Upper urinary tract stone compositions: the role of age and gender
Revista: International braz j urol
Base de datos: PERIÓDICA
Número de sistema: 000434656
ISSN: 1677-5538
Autors: 1
2
1
1
1
Institucions: 1Beijing Tsinghua Changgung Hospital, Department of Urology, Beijing. China
2University of North Carolina, Chapel Hill, Carolina del Norte. Estados Unidos de América
Any:
Període: Ene-Feb
Volum: 46
Número: 1
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Analítico, descriptivo
Resumen en inglés Objective: To analyze the compositions of upper urinary tract stones and investigate their distributions in different gender and age groups. Materials and Methods: Patients diagnosed with upper urinary tract stone disease between December 2014 and March 2018 were retrospectively reviewed. Patient's age, gender, BMI, comorbidities, stone event characteristics, and compositions were collected, and proportions of stone components in different gender and age groups were analyzed. Results: A total of 1532 stone analyses were performed (992 from males and 540 from females). The mean age was younger in males (p <0.001). Males included more cases with larger BMI, hyperuricemia, and obesity, while females had more urinary tract infections. Multiple components were present in 61.8% of stones. Calcium oxalate (CaOx) (67.0%) was the most common component, followed by uric acid (UA) (11.8%), infection stone (11.4%), calcium phosphate (CaP) (8.0%), cystine (1.1%), brushite (0.4%), and 2, 8-dihydroxyadenine (0.2%). Men contributed with more CaOx stones than women at age 30-49 years (all p <0.01) and more UA stones at 30-59 years (all p <0.05). Women contributed with more infection stones than men in age groups 30-49 and 60-69 years (all p <0.05), and more CaP stones at 30-49 years. The prevalence peak was 50-59 years in men and 60-69 years in women. Both genders had the lowest prevalence in adolescence. Prevalence of UA stones increased while that of infection stones decreased with aging in both genders. Conclusions: Age and sex had a strong association with distribution of stone compositions in this Chinese cohort
Disciplines Medicina
Paraules clau: Urología,
Cálculos urinarios,
Grupos etarios,
Género
Keyword: Urology,
Urinary tract stones,
Age groups,
Gender
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