| Revista: | International braz j urol |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000434672 |
| ISSN: | 1677-5538 |
| Autors: | Sánchez Basto, Catalina1 Puerto Niño, Katherine Angie1 Fernández, Nicolás2 Castillo, Mariangel3 Espitaleta Vergara, Zilac4 Quintero Gómez, Ana María5 Pérez Niño, Jaime2 |
| Institucions: | 1Pontificia Universidad Javeriana, Bogotá. Colombia 2Pontificia Universidad Javeriana, Hospital Universitario San Ignacio, Bogotá. Colombia 3Hospital Universitario San Ignacio, Departamento de Nefrología, Bogotá. Colombia 4Hospital Universitario San Ignacio, Departamento de Epidemiología Clínica, Bogotá. Colombia 5Universidad del Bosque, Departamento de Nefrología, Bogotá. Colombia |
| Any: | 2019 |
| Període: | Nov-Dic |
| Volum: | 45 |
| Número: | 6 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico, descriptivo |
| Resumen en inglés | Introduction: Children with a solitary post-nephrectomy kidney (SNK) are at potential risk of developing kidney disease later in life. In response to the global decline in the number of nephrons, adaptive mechanisms lead to renal injury. The aim of this study was to determine the prevalence and time of onset of high blood pressure (HBP), proteinuria, glomerular filtration rate (GFR) disruption and renal tubular acidosis (RTA) in children with SNK. Materials and methods: After obtaining the approval from our institution's ethics committee, we reviewed the medical records of patients under 18 years of age who underwent unilateral nephrectomy between January 2005 and December 2015 in three university hospitals. Results: We identified 43 patients, 35 (81.4%) cases of unilateral nephrectomy (UNP) were due to a non-oncologic pathology and Wilm's tumor was identified in 8 (18.6%) cases. In patients with non-oncologic disease, 9.3% developed de novo hypertension, with an average time of onset of 7.1 years, 25% developed proteinuria de novo, with an average time of onset of 2.2 years. For GFR, 21.8% presented deterioration of the GFR in an average time of 3.4 years. Ten (43.5%) patients developed some type of de novo renal injury after UNP. Patients with oncologic disease developed the conditions slowly and none of them developed proteinuria. Conclusions: Taking into account the high rate of long term postoperative renal injury, it can be considered that nephrectomy does not prevent this disease. The follow-up of children with SNK requires a multidisciplinary approach and long-term surveillance to detect renal injury |
| Disciplines | Medicina |
| Paraules clau: | Nefrología, Pediatría, Nefrectomía, Insuficiencia renal, Postoperatorio |
| Keyword: | Nephrology, Pediatrics, Postoperative period, Renal insufficiency, Nephrectomy |
| Text complet: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
