| Revista: | International braz j urol |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000434670 |
| ISSN: | 1677-5538 |
| Autors: | Afkari, Rouhi1 Feizabadi, Mohammad Mehdi2 Ansari Moghadam, Alireza3 Safari, Tahereh4 Bokaeian, Mohammad1 |
| Institucions: | 1Zahedan University of Medical Sciences, Infectious Diseases and Tropical Medicine Research Center, Zahedan, Sistan and Baluchistan. Irán 2Tehran University of Medical Sciences, Teherán. Irán 3Zahedan University of Medical Sciences, Health Promotion Research Center, Zahedan, Sistan And Baluchistan. Irán 4Zahedan University of Medical Sciences, Zahedan, Sistan And Baluchistan. Irán |
| Any: | 2019 |
| Període: | Nov-Dic |
| Volum: | 45 |
| Número: | 6 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico, descriptivo |
| Resumen en inglés | Objective: Urinary stones with oxalate composition can cause kidney failure. Recent findings evidenced that probiotics are effective in reducing oxalate absorption in these subjects based on their high colonic absorption levels at baseline. The purpose of this study was to evaluate the effect of the simultaneous use of oxalate-degrading bacteria, Urtica dioica and T. terrestris extract in reducing urinary oxalate. Materials and Methods: Anti-urolithiatic activity of Urtica dioica and T. terrestris extract and probiotic by using ethylene glycol induced rat model. In this study, 4 strains of Lactobacillus and 2 strains of Bifidobacterium and also 2 strains of L. paracasei (that showed high power in oxalate degrading in culture media) were used. Male Wistar rats were divided into four groups (n=6). The rats of group-I received normal diet (positive control group) and groups-II (negative control group), III, IV rats received diet containing ethylene glycol (3%) for 30 days. Groups III rats received Urtica dioica and T. terrestris extract. Groups IV rats received extracts + probiotic for 30 days. Findings: The results show that the use of herbal extracts (Urtica dioica and T. terrestris) reduced the level of urinary oxalate and other parameters of urine and serum. Also, the accumulation of calcium oxalate crystals in the kidney tissue was significantly reduced. Conclusion: Considering that the formation of calcium oxalate crystals can cause inflammation and tissue damage in the kidney, the use of herbal extracts with oxalate degrading bacteria can be a new therapeutic approach to preventing the formation of kidney stones |
| Disciplines | Medicina |
| Paraules clau: | Medicina alternativa, Nefrología, Oxalato de calcio, Orina, Proteínas catiónicas, Probióticos |
| Keyword: | Alternative medicine, Nephrology, Calcium oxalate, Urine, Probiotics, Cationic proteins |
| Text complet: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
