Metabolic investigation of patients with urolithiasis in a specific region



Título del documento: Metabolic investigation of patients with urolithiasis in a specific region
Revista: International braz j urol
Base de datos: PERIÓDICA
Número de sistema: 000296518
ISSN: 1677-5538
Autors: 1

Institucions: 1Universidade Estadual do Oeste do Parana, Cascavel, Parana. Brasil
Any:
Període: May-Jun
Volum: 29
Número: 3
Paginació: 217-220
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Caso clínico, analítico
Resumen en inglés OBJECTIVE: To assess the prevalence of the main metabolic alterations found in patients with recent diagnosis of urolithiasis in the West region of Paraná state, Brazil. MATERIALS AND METHODS: We made a retrospective study on 425 patients with evidence of recent formation of renal stones. Laboratory assessment consisted in 3 samples of 24-hour urine with dosing of calcium, uric acid, citrate, oxalate, sodium and creatinine. A urine culture was also made and qualitative cystinuria and urinary pH following 12-hour fasting and water restriction were evaluated. RESULTS: In 96.5% of patients a cause was detected for the urolithiasis. Metabolic alterations most frequently found were: hypercalciuria (38.3%), hypocitraturia (29.6%) and hyperexcretion of uric acid (21.6%). Low urinary volume (17.9%), urinary tract infection (12.9%), hyperparathyroidism (3.3%), renal tubular acidosis (1.2%), cystinuria (0.9%) and anatomical alterations (12.7%) were also observed. CONCLUSIONS: Hypercalciuria, hypocitraturia and hyperuricuria are the most frequent metabolic disorders in the population under study and these data are in accordance to the literature
Disciplines Medicina
Paraules clau: Cirugía,
Endocrinología,
Urolitiasis,
Enfermedades metabólicas,
Factores de riesgo,
Oxalato de calcio,
Calcio
Keyword: Medicine,
Endocrinology,
Surgery,
Urolithiasis,
Metabolic diseases,
Risk factors,
Calcium oxalate,
Calcium
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