| Revista: | International braz j urol |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000434744 |
| ISSN: | 1677-5538 |
| Autors: | Viana, Publio Cesar Cavalcanti1 Horvat, Natally1 Santos Júnior, Valter Ribeiro dos1 Lima, Thais Carneiro1 Romão, Davi dos Santos1 Cerri, Luciana Mendes de Oliveira1 Castro, Marilia Germanos de2 Vargas, Herbert Alberto3 Miranda, Júlia Azevedo1 Leite, Claudia da Costa1 Cerri, Giovanni Guido1 |
| Institucions: | 1Hospital Sirio Libanes, Departamento de Radiologia, Sao Paulo. Brasil 2Hospital Sirio Libanes, Departamento de Patologia, Sao Paulo. Brasil 3Memorial Sloan Kettering Cancer Center, Department of Radiology, Nueva York. Estados Unidos de América |
| Any: | 2019 |
| Període: | Jul-Ago |
| Volum: | 45 |
| Número: | 4 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico, descriptivo |
| Resumen en inglés | Objectives To evaluate the diagnostic performance and interobserver agreement of PI-RADS v2. Materials and Methods In this Institutional Review Board approved single-center retrospective study, 98 patients with clinically suspected PCa who underwent 3-T multiparametric MRI followed by MRI/TRUS fusion-guided prostate biopsy were included from June 2013 to February 2015. Two radiologists (R1 and R2) with 8 and 1 years of experience in abdominal radiology reviewed the MRI scans and assigned PI-RADS v2 scores in all prostate zones. PI-RADS v2 were compared to MRI/TRUS fusion-guided biopsy results, which were classified as negative, PCa, and significant PCa (sPCa). Results Sensitivity, specificity, NPV, PPV and accuracy for PCa was 85.7% (same for all metrics) for R1 and 81.6%, 79.6%, 81.2%, 80.0% and 80.6% for R2. For detecting sPCa, the corresponding values were 95.3%, 85.4%, 95.9%, 83.7% and 89.8% for R1 and 93.0%, 81.8%, 93.7%, 86.7% and 86.7% for R2. There was substantial interobserver agreement in assigning PI-RADS v2 score as negative (1, 2, 3) or positive (4, 5) (Kappa=0.78). On multivariate analysis, PI-RADS v2 (p <0.001) was the only independent predictor of sPCa compared with age, abnormal DRE, prostate volume, PSA and PSA density. Conclusions Our study population demonstrated that PI-RADS v2 had high diagnostic accuracy, substantial interobserver agreement, and it was the only independent predictor of sPCa |
| Disciplines | Medicina |
| Paraules clau: | Oncología, Urología, Diagnóstico, Próstata, Neoplasias, Radiología, Imagenología por resonancia magnética |
| Keyword: | Oncology, Urology, Diagnosis, Prostate, Neoplasms, Magnetic resonance imaging, Radiology |
| Text complet: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
