| Revista: | International braz j urol |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000434907 |
| ISSN: | 1677-5538 |
| Autors: | Mussi, Thais Caldara1 Martins, Tatiana1 Dantas, George Caldas1 Garcia, Rodrigo Gobbo2 Filippi, Renee Zon3 Lemos, Gustavo Caserta4 Baroni, Ronaldo Hueb1 |
| Institucions: | 1Hospital Israelita Albert Einstein, Departamento de Radiologia e Diagnostico por Imagem, Sao Paulo. Brasil 2Hospital Israelita Albert Einstein, Departamento de Intervencao Guiada por Imagens, Sao Paulo. Brasil 3Hospital Israelita Albert Einstein, Departamento de Patologia, Sao Paulo. Brasil 4Hospital Israelita Albert Einstein, Departamento de Urologia, Sao Paulo. Brasil |
| Any: | 2018 |
| Període: | Nov-Dic |
| Volum: | 44 |
| Número: | 6 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico, descriptivo |
| Resumen en inglés | Background: Dynamic-contrast enhanced (DCE) sequence is used to increase detection of small lesions, based on increased vascularization. However, literature is controversy about the real incremental value of DCE in detection of clinically significant (CS) prostate cancer (PCa), since absence of enhancement does not exclude cancer, and enhancement alone is not definitive for tumor. Purpose: To test the hypothesis that DCE images do not increase CS PCa detection on MRI prior to biopsy, comparing exams without and with contrast sequences. Material and Materials and Methods: All men who come to our institution to perform MRI on a 3T scanner without a prior diagnosis of CS PCa were invited to participate in this study. Reference standard was transrectal prostate US with systematic biopsy and MRI/US fusion biopsy of suspicious areas. Radiologists read the MRI images prospectively and independently (first only sequences without contrast, and subsequently the entire exam) and graded them on 5-points scale of cancer suspicion. Results: 102 patients were included. Overall detection on biopsy showed CS cancer in 43 patients (42.2%), clinically non-significant cancer in 11 (10.8%) and negative results in 48 patients (47%). Positivities for CS PCa ranged from 8.9% to 9.8% for low suspicion and 75.0% to 88.9% for very high suspicion. There was no statistical difference regarding detection of CS PCa (no statistical difference was found when compared accuracies, sensitivities, specificities, PPV and NPV in both types of exams). Inter-reader agreement was 0.59. Conclusion: Exams with and without contrast-enhanced sequences were similar for detection of CS PCa on MRI |
| Disciplines | Medicina |
| Paraules clau: | Oncología, Urología, Diagnóstico, Neoplasias, Próstata, Imagenología por resonancia magnética |
| Keyword: | Oncology, Urology, Diagnosis, Neoplasms, Prostate, Magnetic resonance imaging |
| Text complet: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
