Revista: | International braz j urol |
Base de datos: | PERIÓDICA |
Número de sistema: | 000296478 |
ISSN: | 1677-5538 |
Autors: | Mangini, Marcelo1 Dall'Oglio, Marcos F Srougi, Miguel Ribeiro, Eduardo Ferraz, Marcio Sanudo, Adriana Leite, Katia Nesrallah, Luciano |
Institucions: | 1Universidade Federal de Sao Paulo, Escola Paulista de Medicina, Sao Paulo. Brasil |
Any: | 2003 |
Període: | Mar-Abr |
Volum: | 29 |
Número: | 2 |
Paginació: | 106-112 |
País: | Brasil |
Idioma: | Inglés |
Tipo de documento: | Artículo |
Enfoque: | Caso clínico, analítico |
Resumen en inglés | INTRODUCTION: Classification TNM 1997 defines renal cell carcinoma smaller than 7 cm and confined to the kidney as stage T1. Our goal is to discuss if tumors smaller than 4 cm have the same behavior characteristics then tumors between 4 and 7 cm, to compose the same stage of the disease. MATERIALS AND METHODS: Retrospective assessment of 138 patients in stage T1 (TNM - 97), divided into 2 groups; group-1: composed of 65 patients (47%) with tumors < 4 cm, and group-2: composed of 73 patients (53%) with tumors between 4 and 7 cm. The following prognostic factors were assessed in the recurrence of the disease and survival of patients: nuclear degree, microvascular invasion, sarcomatous degeneration, and involved lymph nodes. Statistical evaluation has been accomplished through the log rank test, chi-square test, and Fishers exact text. RESULTS: Average tumor size was 2.5 cm for group-1, and 5.3 cm for group-2. In group-2, there was the predominance of worse prognostic factors, with high-grade tumors (p = 0.01) and presence of microvascular invasion (p = 0.001). Sarcomatous tumors and involvement of lymph nodes did only happen in group-2. Disease-free survival for group-1, analyzed in the median period of 36 months, was 100%, and for group 2, in the median period of 31 months, was 81% (p = 0.008). CONCLUSION: The results obtained allow the conclusion that the present stage T1 for renal cell carcinoma gathers tumors of different evolution, being therefore recommendable the stratification in T1a for tumors smaller than 4 cm, and T1b f |
Disciplines | Medicina |
Paraules clau: | Cirugía, Nefrología, Riñones, Células renales, Carcinoma, Neoplasias, Clasificación, Sobrevivencia, Prognóstico |
Keyword: | Medicine, Nephrology, Surgery, Kidneys, Renal cells, Carcinoma, Neoplasms, Classification, Survival, Prognosis |
Text complet: | Texto completo (Ver HTML) |