Spray-drying technique to prepare innovative nanoparticulated formulations for drug administration: a brief overview



Título del documento: Spray-drying technique to prepare innovative nanoparticulated formulations for drug administration: a brief overview
Revista: Brazilian journal of physics
Base de datos: PERIÓDICA
Número de sistema: 000403109
ISSN: 0103-9733
Autors: 1
2
3
Institucions: 1Universidade Federal do Rio Grande do Sul, Faculdade de Farmacia, Porto Alegre, Rio Grande do Sul. Brasil
2Universidade Federal de Santa Maria, Centro de Ciencias da Saude, Santa Maria, Rio Grande do Sul. Brasil
3Universidade Federal do Rio Grande do Sul, Departamento de Quimica Organica, Porto Alegre, Rio Grande do Sul. Brasil
Any:
Període: Abr
Volum: 39
Número: 1A
Paginació: 205-209
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Analítico
Resumen en inglés Polymeric nanoparticle systems (nanocapsules and nanospheres) present potential applications as drug delivery systems. Nevertheless, their full applications have not been exploited due to their limited shelf life when stored in aqueous medium. Drying polymeric nanoparticles using spray-drying represents a promising platform to improve the physicochemical stability of formulations and/or to control the release of hydrophilic and lipophilic drugs. This article presents a brief overview of the most recent and ongoing research in the use of spray-drying process to prepare and/or to dry polymeric nanoparticles formulations intended for drug administration
Disciplines Química
Paraules clau: Química farmacéutica,
Polímeros,
Nanopartículas
Keyword: Chemistry,
Medicinal chemistry,
Polymers,
Nanoparticles
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